PEA15

Gene Symbol	PEA15
Entrez Gene	8682
Alt Symbol	HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED
Species	Human
Gene Type	protein-coding
Description	phosphoprotein enriched in astrocytes 15
Other Description	15 kDa phosphoprotein enriched in astrocytes|astrocytic phosphoprotein PEA-15|homolog of mouse MAT-1 oncogene|mammary transforming gene 1, mouse, homolog of|phosphoprotein enriched in diabetes
Swissprots	O00511 B1AKZ3 Q15121
Accessions	AAD56775 EAW52733 EAW52734 EAW52735 Q15121 AA837443 AI948916 AK095879 BAG53155 AK311762 BAG34705 BC002426 AAH02426 BC010469 AAH10469 BC022554 AAH22554 BT007252 AAP35916 CR541733 CAG46533 DA131259 DA157938 DA532423 DA538845 DA707281 DQ891821 ABM82747 DQ891824 ABM82750 DQ895008 ABM85934 HY182028 L37385 AAA98120 X86809 CAA60499 Y13736 CAA74076 XM_006711599 XP_006711662 NM_001297576 NP_001284505 NM_001297577 NP_001284506 NM_001297578 NP_001284507 NM_003768 NP_003759 NR_123724
Function	Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface. {ECO:0000250, ECO:0000269|PubMed:10442631, ECO:0000269|PubMed:9670003}.
Subcellular Location	Cytoplasm. Note=Associated with microtubules.
Tissue Specificity	Ubiquitously expressed. Most abundant in tissues such as heart, brain, muscle and adipose tissue which utilize glucose as an energy source. Lower expression in glucose- producing tissues. Higher levels of expression are found in tissues from individuals with type 2 diabetes than in controls. {ECO:0000269|PubMed:9670003}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PEA15 full length protein - ab172828 from Abcam Category Protein Source E. coli Species Human

Human PEA15 full length protein - ab87717 from Abcam Category Protein Source E. coli Species Human

Human PEA15 full length protein - ab117660 from Abcam Category Protein Source E. coli Species Human

PEA15 / PEA-15 Antibody Blocking Peptide - LS-E21559 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PEA15 / PEA-15 Antibody Blocking Peptide - LS-E9620 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PEA15 / PEA-15 Antibody Blocking Peptide - LS-E17453 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PEA-15 Protein - NBP1-30247 from Novus Biologicals Category Protein Prices $499.00 Sizes 100 µg Source E.coli Species Human

PEA-15 Recombinant Protein - P3400 from Novus Biologicals Category Protein Prices $1,049.00 Sizes 100 µg Species Human

PEA-15-Antibody-C-term-Blocking-Peptide - BP8524b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PEA15 Protein (OPPA02196) - OPPA02196 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human Phosphoprotein Enriched in Astrocytes 15 protein - orb81267 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E.coli

Human PEA15 R protein - orb163502 from Biorbyt Category Protein Prices $323.00, $485.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source E. coli Species Human

PEA15 Blocking Peptide - 33R-2058 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PEA15 Blocking Peptide - 33R-2246 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PEA15 protein - 30R-1399 from Fitzgerald Category Protein Prices $515.00 Sizes 100 µg Source E.coli

PEA15 (1-130) - AR09282PU-L from Acris Antibodies Category Protein Prices $1,470.00 Sizes 500 µg Source E. coli Species Human

PEA15 (1-130) - AR09282PU-N from Acris Antibodies Category Protein Prices $570.00 Sizes 100 µg Source E. coli Species Human

PEA15 - P3400 from Acris Antibodies Category Protein Prices $840.00 Sizes 100 µg Species Human

Phosphoprotein Enriched in Astrocytes 15, Human Recombinant - 228-13184-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Phosphoprotein Enriched in Astrocytes 15 - 228-13184-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Phosphoprotein Enriched in Astrocytes 15 - 228-13184-3 from RayBiotech Category Protein Source Escherichia Coli. Species Human

PEA-15, 1-130 aa, Human, Recombinant, E.coli - 01-2176-15 from ARP American Research Products Category Protein Prices $229.00, $230.00, $609.00 Sizes 20 µg, 500 µg, 100 µg Source E.coli Species Human

PEA15, Human, Recombinant - 19-CF65 from ARP American Research Products Category Protein Prices $119.00 Sizes 10 µg Source E. coli Species Human

PEA15 fusion protein - Ag13782 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

PEA15 fusion protein - ag13721 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

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