HSP90AB1

Gene Symbol	HSP90AB1
Entrez Gene	3326
Alt Symbol	D6S182, HSP84, HSP90B, HSPC2, HSPCB
Species	Human
Gene Type	protein-coding
Description	heat shock protein 90kDa alpha (cytosolic), class B member 1
Other Description	HSP90-beta|heat shock 84 kDa|heat shock 90kD protein 1, beta|heat shock protein HSP 90-beta
Swissprots	Q5T9W7 P08238 Q9NQW0 Q9NTK6 B2R5P0
Accessions	AAA36026 ABC40731 BAA22050 EAX04257 EAX04258 EAX04259 EAX04260 P08238 AF275719 AAF82792 AK025370 BAB15121 AK130494 AK290734 BAF83423 AK294643 BAG57821 AK297367 BAG59814 AK312255 BAG35187 AL136543 CAB66478 AY359878 AAQ63401 BC004928 AAH04928 BC007327 AAH07327 BC009206 AAH09206 BC012807 AAH12807 BC014485 AAH14485 BC016753 AAH16753 BC068474 AAH68474 BE539681 BG482327 BI252490 BQ028821 BX420114 BX649079 CD653541 CX761569 D28342 BAA05708 DC340766 DC341882 DC350708 DC365600 DQ893024 ABM83950 DQ896268 ABM87267 M16660 AAA36025 NM_001271969 NP_001258898 NM_001271970 NP_001258899 NM_001271971 NP_001258900 NM_001271972 NP_001258901 NM_007355 NP_031381 NR_073528
Function	Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. {ECO:0000269|PubMed:16478993, ECO:0000269|PubMed:19696785}.
Subcellular Location	Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Top Pathways	Progesterone-mediated oocyte maturation, Prostate cancer, NOD-like receptor signaling pathway, Protein processing in endoplasmic reticulum, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SimpleChIP ® Human HSP90β Promoter Primers - 12899 from Cell Signaling Technology Category ChIP Kit Prices $102.00 Sizes 500 µl (250 PCR reactions)

Mouse/Human/Rat HSP90AB1 / HSP90 Alpha B1 ELISA Kit (Cell-Based ELISA) - LS-F2065 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 ng/ml

Mouse/Human/Rat Phospho-HSP90AB1 / HSP90 Alpha B1 (Ser254) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1041 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 ng/ml

Rat HSP90AB1 / HSP90 Alpha B1 ELISA Kit (Sandwich ELISA) - LS-F9054 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.56 ng/ml Range 0.156-10 ng/ml

Human HSP90AB1 / HSP90 Alpha B1 ELISA Kit (Sandwich ELISA) - LS-F9053 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.56 ng/ml Range 0.156-10 ng/ml

Bovine HSP90AB1 / HSP90 Alpha B1 ELISA Kit (Sandwich ELISA) - LS-F8840 from LifeSpan Bioscience Category ELISA Kit Prices $860.00 Sizes 1 plate Sensitivity 0.059 ng/ml Range 0.156-10 ng/ml

Mouse HSP90AB1 / HSP90 Alpha B1 ELISA Kit (Sandwich ELISA) - LS-F9960 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 1.56 ng/ml Range 0.156-10 ng/ml

Human HSP90aB1 ELISA Kit - abx151859 from Abbexa Category ELISA Kit Sensitivity 0.67 ng/ml Range 1.563 ng/ml - 100 ng/ml

Heat Shock Protein 90kDa Alpha B1 (HSP90aB1), Human, ELISA Kit - SED522Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.67ng/mL Range 1.56-100ng/mL

Heat shock protein HSP 90-beta (HSP90AB1), Human, ELISA Kit - CSB-EL010808HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

heat shock protein 90kDa alpha (cytosolic) , class B member 1, ELISA Kit - MBS911007 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human HSP90AB1 is typically less than 0.39 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 1.56 ng/ml -100 ng/ml.

Heat shock protein HSP 90-beta, ELISA Kit - MBS280701 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hsp90 Antibody and Protein Pack - SPK-210 from StressMarq Bioscience Prices $664.00 Sizes 13x 25ug Sensitivity N/A Range N/A

Hsp90 Antibody Pack - SPK-200 from StressMarq Bioscience Prices $582.00 Sizes 11x 25ug Sensitivity N/A Range N/A

HSP90B Colorimetric Cell-Based ELISA Kit - CB5352 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

HSP90B (Phospho-Ser254) Colorimetric Cell-Based ELISA Kit - CBP1013 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

ELISA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) - SED522Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.59ng/mL. Range 1.56-100ng/mL The standard curve concentrations used for the ELISA’s were 100ng/mL, 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.13ng/mL, 1.56ng/mL

ELISA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) - SED522Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.59ng/mL. Range 1.56-100ng/mL The standard curve concentrations used for the ELISA’s were 100ng/mL, 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.13ng/mL, 1.56ng/mL

ELISA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) - SED522Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.56ng/mL. Range 1.56-100ng/mL The standard curve concentrations used for the ELISA’s were 100ng/mL, 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.13ng/mL, 1.56ng/mL

Human Heat shock protein HSP 90-beta(HSP90AB1) ELISA kit - CSB-EL010808HU from Cusabio Category ELISA Kit Sensitivity 0.39 ng/ml Range 1.56 ng/ml-100 ng/ml

ELISA Kit for Heat Shock Protein 90kDa Alpha B1 (HSP90aB1) - SED522Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.59ng/mL. Range 1.563-100ng/mL The standard curve concentrations used for the ELISA's were 100ng/mL, 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL

Heat Shock Protein 90kDa Alpha B1 (HSP90aB1), Human, ELISA Kit - DL-HSP90aB1-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 1.56-100 ng/mL

HSP90B ELISA Kit - DEIA-XYA837 from Creative Diagnostics Category ELISA Kit

HSP90B (Phospho-Ser254) ELISA Kit - DEIA-XYA838 from Creative Diagnostics Category ELISA Kit

Human HSP90AB1 ELISA Kit - E018025 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human HSP90AB1 is typically less than 0.39 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the

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