HSP90AB1

Gene Symbol	HSP90AB1
Entrez Gene	3326
Alt Symbol	D6S182, HSP84, HSP90B, HSPC2, HSPCB
Species	Human
Gene Type	protein-coding
Description	heat shock protein 90kDa alpha (cytosolic), class B member 1
Other Description	HSP90-beta|heat shock 84 kDa|heat shock 90kD protein 1, beta|heat shock protein HSP 90-beta
Swissprots	Q5T9W7 P08238 Q9NQW0 Q9NTK6 B2R5P0
Accessions	AAA36026 ABC40731 BAA22050 EAX04257 EAX04258 EAX04259 EAX04260 P08238 AF275719 AAF82792 AK025370 BAB15121 AK130494 AK290734 BAF83423 AK294643 BAG57821 AK297367 BAG59814 AK312255 BAG35187 AL136543 CAB66478 AY359878 AAQ63401 BC004928 AAH04928 BC007327 AAH07327 BC009206 AAH09206 BC012807 AAH12807 BC014485 AAH14485 BC016753 AAH16753 BC068474 AAH68474 BE539681 BG482327 BI252490 BQ028821 BX420114 BX649079 CD653541 CX761569 D28342 BAA05708 DC340766 DC341882 DC350708 DC365600 DQ893024 ABM83950 DQ896268 ABM87267 M16660 AAA36025 NM_001271969 NP_001258898 NM_001271970 NP_001258899 NM_001271971 NP_001258900 NM_001271972 NP_001258901 NM_007355 NP_031381 NR_073528
Function	Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. {ECO:0000269|PubMed:16478993, ECO:0000269|PubMed:19696785}.
Subcellular Location	Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Top Pathways	Progesterone-mediated oocyte maturation, Prostate cancer, NOD-like receptor signaling pathway, Protein processing in endoplasmic reticulum, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Hsp90 beta full length protein - ab80033 from Abcam Category Protein Prices $239.00 Sizes 50 µg Source Baculovirus infected High-5 cells Species Human

Human Hsp90 beta full length protein - ab131923 from Abcam Category Protein Source Wheat germ Species Human

Human Hsp90 beta full length protein - ab157026 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human Hsp90 beta full length protein - ab80353 from Abcam Category Protein Source E. coli Species Human

Human Hsp90 beta full length protein - ab52154 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human Hsp90 beta peptide - ab87826 from Abcam Category Peptide

HSP90AB1 / HSP90 Alpha B1 Antibody Blocking Peptide - LS-E10516 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HSP90AB1 / HSP90 Alpha B1 Antibody Blocking Peptide - LS-E10592 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HSP90AB1 / HSP90 Alpha B1 Antibody Blocking Peptide - LS-E21532 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HSP90AB1 / HSP90 Alpha B1 Antibody Blocking Peptide - LS-E9326 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HSP90AB1 / HSP90 Alpha B1 Antibody Blocking Peptide - LS-E9327 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human HSP90 beta Protein - H00003326-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human HSP90 beta Protein - NBP1-99576 from Novus Biologicals Category Protein Prices $275.00 Sizes 25 µg Source Sf9 cells Species Human

HSP90 beta Protein - NBP1-99575 from Novus Biologicals Category Protein Prices $399.00 Sizes 25 µg Species Human

HSP90 beta Protein - NBP1-99771 from Novus Biologicals Category Protein Species Human

HSP90 beta Protein - NBP1-99770 from Novus Biologicals Category Protein Species Human

HSP90AB1-Antibody-Center-Blocking-Peptide - BP7867d from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HSP90AB1-Antibody-C-term-Blocking-Peptide - BP7867b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human HSP90AB1 protein - orb83718 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source E. coli Species Human

HSP90AB1 Blocking Peptide - 33R-6274 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

HSP90AB1 Blocking Peptide - 33R-1357 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human HSP90aB1 Protein - abx067018 from Abbexa Category Protein Source E.coli Species Human

HSP90AB1 / HSP90 beta - H00003326-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

HSP90AB1 / HSP90 beta - H00003326-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Heat Shock Protein 90kDa Alpha B1 (HSP90aB1), Human - 20-8811 from ARP American Research Products Category Protein Prices $369.00 Sizes 50 µg Source E.coli Species Human

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