DHFRL1

Gene Symbol	DHFRL1
Entrez Gene	200895
Alt Symbol	DHFRP4
Species	Human
Gene Type	protein-coding
Description	dihydrofolate reductase-like 1
Other Description	dihydrofolate reductase pseudogene 4|dihydrofolate reductase, mitochondrial|dihydrofolate reductase-like protein 1
Swissprots	Q6P4I9 D3DN30 Q86XF0
Accessions	EAW79895 EAW79896 Q86XF0 AK122674 BAG53658 AL832912 CAH10617 AW104373 BC045541 AAH45541 BC063379 AAH63379 HQ447989 ADQ32471 XM_011512537 XP_011510839 NM_001195643 NP_001182572 NM_176815 NP_789785
Function	Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR. {ECO:0000269|PubMed:21876184, ECO:0000269|PubMed:21876188}.
Subcellular Location	Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane.
Tissue Specificity	Expressed in numerous cell lines. {ECO:0000269|PubMed:21876184}.
Top Pathways	Folate biosynthesis, One carbon pool by folate

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DHFRL1-Over-expression-Lysate - LY15452a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

DHFRL1 293T Cell Transient Overexpression Lysate(Denatured) - H00200895-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

DHFRL1 293 Cell Lysate - 403798 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

DHFRL1 Overexpression Lysate (Denatured) - H00200895-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

DHFRL1 Overexpression Lysate (Native) - NBL1-09861 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

DHFRL1 Over-expression Lysate Product - GWB-11686C from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human DHFRL1 Knockdown Stable Cell Line - CSC-DC004266 from Creative biogene Category Cell Line Species Human

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