PXK

Gene Symbol PXK
Entrez Gene 54899
Alt Symbol MONaKA
Species Human
Gene Type protein-coding
Description PX domain containing serine/threonine kinase
Other Description PX domain-containing protein kinase-like protein|PX ser/thr kinase v2|PX serine/threonine kinase|modulator of Na,K-ATPase long form
Swissprots Q3BCH4 Q6ZN39 Q3BDW1 Q7Z7A4 Q59EX3 Q96R07 Q45L83 Q6PK17 Q9NXB8 Q96CA3 Q3BCH5 Q3BCH6
Accessions EAW65368 EAW65369 EAW65370 Q7Z7A4 AB209688 BAD92925 AF399753 AAK94455 AK000342 BAA91097 AK124775 AK131385 BAD18536 AK295542 BAG58451 AK296034 BAG58800 AK296215 BAG58940 AL137938 AY274811 AAP42076 AY437879 AAR98521 AY847220 AAX73352 AY847221 AAX73353 AY847222 AAX73354 BC008943 AAH08943 BC014479 AAH14479 BC108670 AAI08671 BG613223 DA296189 DQ124707 AAZ38821 DQ124708 AAZ38822 HY164612 KF774202 AHG94944 KF774203 AHG94945 KF774204 AHG94946 XM_005265250 XP_005265307 XM_005265252 XP_005265309 XM_005265255 XP_005265312 XM_005265256 XP_005265313 XM_011533864 XP_011532166 XM_011533865 XP_011532167 XM_011533866 XP_011532168 XM_011533867 XP_011532169 XM_011533868 XP_011532170 XR_940460 XR_940461 XR_940462 XR_940463 NM_001289095 NP_001276024 NM_001289096 NP_001276025 NM_001289098 NP_001276027 NM_001289099 NP_001276028 NM_001289100 NP_001276029 NM_001289101 NP_001276030 NM_017771 NP_060241
Function Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity. {ECO:0000250|UniProtKB:Q8BX57, ECO:0000303|PubMed:16142408}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:16142408}. Cell membrane {ECO:0000269|PubMed:16142408}; Peripheral membrane protein {ECO:0000269|PubMed:16142408}. Note=Also associates with the plasma membrane. Isoform 3 is present throughout the cell.
Tissue Specificity Widely expressed in all tissues examined except in heart. Isoform 1 is expressed in high levels in the brain, skeletal muscle, spleen and testis. Isoform 7 expression has yet to be demonstrated. {ECO:0000269|PubMed:16142408}.

PXK (D-6) - sc-377077 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PXK (D-6): sc-377077. Western blot analysis of PXK expression in LADMAC whole cell lysate.

PXK (P-14) - sc-100108 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PXK (P-14): sc-100108. Western blot analysis of PXK expression in mouse brain tissue extract.

PXK (Q-16) - sc-100109 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PXK (Q-16): sc-100109. Western blot analysis of PXK expression in mouse brain tissue extract.

PXK (K-19) - sc-100107 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PXK (K-19): sc-100107. Western blot analysis of PXK expression in LADMAC (A) and KNRK (B) whole cell lysates.

PXK (H-300) - sc-366664 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-PXK antibody - ab67923 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-PXK antibody (ab67923) at 1/500 dilution + Rat brain lysate at 25 µgSecondaryGoat anti-mouse IgG(H&L)-HRP at 1/2500 dilution

Anti-PXK antibody - ab116518 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PXK antibody (ab116518) at 1/100 dilution + Jurkat cell line lysate at 35 µg

Anti-PXK antibody - ab71397 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PXK antibody (ab71397) at 1/60 dilution + Hela cell line lysate at 35 µg

Anti-PXK Antibody (aa164-193) IHC-plus™ - LS-B11897 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Mouse Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-PXK Antibody (aa163-193, AP) - LS-C267625 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PXK Antibody (aa163-193, APC) - LS-C267627 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PXK Antibody (aa163-193, Biotin) - LS-C267628 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PXK Antibody (aa163-193, FITC) - LS-C267630 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PXK Antibody (aa163-193, Azide-free, HRP) - LS-C267629 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PXK Antibody (aa163-193, PE) - LS-C267631 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PXK Antibody (APC) - LS-C281714 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PXK Antibody (AP) - LS-C281711 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PXK Antibody (Biotin) - LS-C281716 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PXK Antibody (Azide-free, HRP) - LS-C281717 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PXK Antibody (FITC) - LS-C281718 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PXK Antibody (PE) - LS-C281719 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PXK Antibody (aa163-193) - LS-C324436 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PXK Antibody (aa32-132, Azide-free) - LS-C330618 from LifeSpan Bioscience

Host Rabbit
Clonality Monoclonal

Anti-PXK Antibody (Internal) - LS-C98922 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of PXK (arrow) using rabbit polyclonal PXK Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PXK gene.

PXK Antibody - NBP1-83663 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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