PHF10

Gene Symbol	PHF10
Entrez Gene	55274
Alt Symbol	BAF45A, XAP135
Species	Human
Gene Type	protein-coding
Description	PHD finger protein 10
Other Description	BRG1-associated factor 45a|BRG1-associated factor, 45-KD, A|PHD zinc finger protein XAP135
Swissprots	Q8WUB8 Q2YDA3 Q9NV26 Q53HG8 Q9BXD2
Accessions	AAK27451 EAW47442 EAW47443 EAW47444 Q8WUB8 AJ420510 AK001837 BAA91934 AK222612 BAD96332 AK296349 BAG59032 AL133094 BC020954 AAH20954 BC110323 AAI10324 CR457273 CAG33554 DB460742 DQ891432 ABM82358 DQ894607 ABM85533 KC839988 AGQ46690 KC839989 AGQ46691 NM_018288 NP_060758 NM_133325 NP_579866
Function	Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron- specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulatin
Subcellular Location	Nucleus {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PHF10 full length protein - ab132764 from Abcam Category Protein Source Wheat germ Species Human

Human PHF10 protein fragment - ab132765 from Abcam Category Protein Source Wheat germ Species Human

Human PHF10 protein fragment - ab127369 from Abcam Category Protein Source E. coli Species Human

PHF10 Antibody Blocking Peptide - LS-E17655 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PHF10 Protein - H00055274-P02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human PHF10 Protein - H00055274-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PHF10 Blocking Peptide - 33R-7051 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PHF10 - H00055274-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PHF10 - H00055274-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PHF10 - H00055274-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

PHF10 - H00055274-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PHF10 - H00055274-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PHF10 fusion protein - ag10917 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

PHF10 fusion protein - ag19096 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human PHD finger protein 10(PHF10) - CSB-YP017898HU CSB-EP017898HU CSB-BP017898HU CSB-MP017898HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PHF10 (full length, N-term HIS tag, transcript variant 1) - TP760847 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

PHD finger protein 10 (PHF10), Recombinant Protein - MBS1461058 from MyBioSource Category Protein Prices $1,285.00, $1,285.00, $1,500.00, $1,500.00, $2,105.00, $2,105.00, $2,570.00, $2,570.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PHF10 Protein - NBP2-33759PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

PHF10 Peptide, Human - M34GP11685H from Creative Peptides Category Peptide Source Synthetic. Species Human

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