PHF10

Gene Symbol PHF10
Entrez Gene 55274
Alt Symbol BAF45A, XAP135
Species Human
Gene Type protein-coding
Description PHD finger protein 10
Other Description BRG1-associated factor 45a|BRG1-associated factor, 45-KD, A|PHD zinc finger protein XAP135
Swissprots Q8WUB8 Q2YDA3 Q9NV26 Q53HG8 Q9BXD2
Accessions AAK27451 EAW47442 EAW47443 EAW47444 Q8WUB8 AJ420510 AK001837 BAA91934 AK222612 BAD96332 AK296349 BAG59032 AL133094 BC020954 AAH20954 BC110323 AAI10324 CR457273 CAG33554 DB460742 DQ891432 ABM82358 DQ894607 ABM85533 KC839988 AGQ46690 KC839989 AGQ46691 NM_018288 NP_060758 NM_133325 NP_579866
Function Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron- specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulatin
Subcellular Location Nucleus {ECO:0000250}.

PHF10 CRISPR/Cas9 KO Plasmid (h) - sc-410593 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHF10 HDR Plasmid (h) - sc-410593-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHF10 Double Nickase Plasmid (h) - sc-410593-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHF10 Double Nickase Plasmid (h2) - sc-410593-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHF10 CRISPR Activation Plasmid (h) - sc-410593-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHF10 CRISPR Activation Plasmid (h2) - sc-410593-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHF10 Lentiviral Activation Particles (h) - sc-410593-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHF10 Lentiviral Activation Particles (h2) - sc-410593-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHF10 siRNA (h) - sc-95343 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PHF10 shRNA Plasmid (h) - sc-95343-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PHF10 shRNA (h) Lentiviral Particles - sc-95343-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PHF10 RNAi - H00055274-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU117181 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16715 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16715 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PHF10 siRNA (Human) - CRJ0614 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PHF10 RNAi - H00055274-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

PHF10 shRNA Plasmid (Human) - CHJ0614 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PHF10 miRNA 3'UTR clone - MiUTR3H-12737 from Creative biogene

Species Reactivities Human

PHF10 miRNA 3'UTR clone - MiUTR3H-12738 from Creative biogene

Species Reactivities Human
Search more