CD81

Gene Symbol CD81
Entrez Gene 975
Alt Symbol CVID6, S5.7, TAPA1, TSPAN28
Species Human
Gene Type protein-coding
Description CD81 molecule
Other Description 26 kDa cell surface protein TAPA-1|CD81 antigen|CD81 antigen (target of antiproliferative antibody 1)|tetraspanin-28|tspan-28
Swissprots P60033 Q5U0J6 P18582
Accessions ABK41932 EAX02507 EAX02508 P60033 AB209380 BAD92617 AI334163 BC002978 AAH02978 BC093047 AAH93047 BG397506 BP323362 BQ709484 BT019507 AAV38314 BT019508 AAV38315 CB055265 DQ891836 ABM82762 DQ891849 ABM82775 DQ895022 ABM85948 M33680 AAA36663 XM_011520492 XP_011518794 NM_001297649 NP_001284578 NM_004356 NP_004347
Function May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May act as the viral receptor for HCV.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Hematolymphoid, neuroectodermal and mesenchymal tumor cell lines.
Top Pathways B cell receptor signaling pathway, Malaria, Hepatitis C