Gene Symbol |
CD81
|
Entrez Gene |
975
|
Alt Symbol |
CVID6, S5.7, TAPA1, TSPAN28
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
CD81 molecule
|
Other Description |
26 kDa cell surface protein TAPA-1|CD81 antigen|CD81 antigen (target of antiproliferative antibody 1)|tetraspanin-28|tspan-28
|
Swissprots |
P60033 Q5U0J6 P18582
|
Accessions |
ABK41932 EAX02507 EAX02508 P60033 AB209380 BAD92617 AI334163 BC002978 AAH02978 BC093047 AAH93047 BG397506 BP323362 BQ709484 BT019507 AAV38314 BT019508 AAV38315 CB055265 DQ891836 ABM82762 DQ891849 ABM82775 DQ895022 ABM85948 M33680 AAA36663 XM_011520492 XP_011518794 NM_001297649 NP_001284578 NM_004356 NP_004347
|
Function |
May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May act as the viral receptor for HCV.
|
Subcellular Location |
Membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Hematolymphoid, neuroectodermal and mesenchymal tumor cell lines.
|
Top Pathways |
B cell receptor signaling pathway, Malaria, Hepatitis C
|