GRM7

Gene Symbol GRM7
Entrez Gene 2917
Alt Symbol GLUR7, GPRC1G, MGLU7, MGLUR7, PPP1R87
Species Human
Gene Type protein-coding
Description glutamate receptor, metabotropic 7
Other Description metabotropic glutamate receptor 7|protein phosphatase 1, regulatory subunit 87
Swissprots Q8NFS3 Q8NFS4 Q8NFS2 Q14831
Accessions CCQ42994 EAW63933 EAW63934 EAW63935 Q14831 AB209214 BAD92451 AI701722 AK097817 AK123326 AK312488 BAG35390 AW511101 BC136458 AAI36459 BC136459 AAI36460 X94552 CAA64245 XM_011533648 XP_011531950 XR_940422 NM_000844 NP_000835 NM_181874 NP_870989 NM_181875
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. {ECO:0000269|PubMed:9473604}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Expressed in many areas of the brain, especially in the cerebral cortex, hippocampus, and cerebellum. Expression of GRM7 isoforms in non-neuronal tissues appears to be restricted to isoform 3 and isoform 4. {ECO:0000269|PubMed:12052533, ECO:0000269|PubMed:8840028}.
Top Pathways Glutamatergic synapse, Neuroactive ligand-receptor interaction

mGluR-7 (H-47) - sc-99045 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

mGluR-7 (N-19) - sc-47156 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Metabotropic Glutamate Receptor 7 antibody - ab53705 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Metabotropic Glutamate Receptor 7 was immunoprecipitated using 0.5mg Rat Brain tissue extract, 5µg of Rabbit polyclonal to Metabotropic Glutamate Receptor 7 and 50µl of protein G magnetic beads (+). No antibody was added to the control (-).The antibody was incubated under agitation with Protein G beads for 10min, Rat Brain tissue extract lysate diluted in RIPA buffer was added to each sample and incubated for a further 10min under agitation.Proteins were eluted by addition of 40µl SDS loading buffer and incubated for 10min at 70°C; 10µl of each sample was separated on a SDS PAGE gel, transferred to a nitrocellulose membrane, blocked with 5% BSA and probed with ab53705.Secondary: Mouse monoclonal [SB62a] Secondary Antibody to Rabbit IgG light chain (HRP) (ab99697).Band: 110kDa; Metabotropic Glutamate Receptor 7

Anti-Metabotropic Glutamate Receptor 7 antibody - ab85343 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-Metabotropic Glutamate Receptor 7 antibody (ab85343) at 0.5 µg/ml + Human Cerebellum lysate at 35 µg

Anti-Metabotropic Glutamate Receptor 7 antibody - ab130491 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Metabotropic Glutamate Receptor 7 antibody (ab130491) at 1/100 dilution + 293 cell line lysate at 35 µg

Anti-Metabotropic Glutamate Receptor 7 antibody - ab136823 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Metabotropic Glutamate Receptor 7 antibody (ab136823) at 1/500 dilution + HUVEC cell lysate at 30 µg

Anti-Metabotropic Glutamate Receptor 7 antibody - ab55066 from Abcam

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab55066 Metabotropic Glutamate Receptor 7 antibody at 1ug/ml.

Anti-GRM7 / MGLUR7 Antibody (aa899-912) - LS-C16553 from LifeSpan Bioscience

Prices $560.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-GRM7 / MGLUR7 Antibody (C-Terminus) - LS-C72514 from LifeSpan Bioscience

Prices $485.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal

Anti-GRM7 / MGLUR7 Antibody (C-Terminus) - LS-C72515 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-GRM7 / MGLUR7 Antibody (phospho-Ser862) - LS-C150365 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GRM7 / MGLUR7 Antibody (aa373-386) - LS-C112826 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
GRM7 antibody (0.5 ug/ml) staining of Human Cerebellum lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-GRM7 / MGLUR7 Antibody (Extracellular Domain) IHC-plus™ - LS-A2694 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GRM7 / MGLUR7 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A2694 dilution 10 ug/ml.

Anti-GRM7 / MGLUR7 Antibody (C-Terminus) - LS-C135563 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GRM7 / MGLUR7 antibody LS-C135563 Western blot of 721_B cell lysate.

Anti-GRM7 / MGLUR7 Antibody (aa240-269, AP) - LS-C258076 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRM7 / MGLUR7 Antibody (N-Terminus) IHC-plus™ - LS-A918 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GRM7 / MGLUR7 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A918 dilution 4-6 ug/ml.

Anti-GRM7 / MGLUR7 Antibody (aa899-912) - LS-C152744 from LifeSpan Bioscience

Prices $475.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal
WB: Rat brain microsomal protein preparation probed with anti-mGluR7 (0.5 micrograms/ml).

Anti-GRM7 / MGLUR7 Antibody (aa351-400) - LS-C120728 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of A549 cells, using GRM7 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-GRM7 / MGLUR7 Antibody (aa866-915) - LS-C118467 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human brain tissue, using mGluR7 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-GRM7 / MGLUR7 Antibody (aa240-269, APC) - LS-C258077 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRM7 / MGLUR7 Antibody (aa240-269, Biotin) - LS-C258078 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRM7 / MGLUR7 Antibody (aa240-269, FITC) - LS-C258079 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRM7 / MGLUR7 Antibody (aa240-269, Azide-free, HRP) - LS-C258080 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRM7 / MGLUR7 Antibody (aa240-269, PE) - LS-C258082 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRM7 / MGLUR7 Antibody (aa340-389) - LS-C292047 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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