GRM7

Gene Symbol	GRM7
Entrez Gene	2917
Alt Symbol	GLUR7, GPRC1G, MGLU7, MGLUR7, PPP1R87
Species	Human
Gene Type	protein-coding
Description	glutamate receptor, metabotropic 7
Other Description	metabotropic glutamate receptor 7|protein phosphatase 1, regulatory subunit 87
Swissprots	Q8NFS3 Q8NFS4 Q8NFS2 Q14831
Accessions	CCQ42994 EAW63933 EAW63934 EAW63935 Q14831 AB209214 BAD92451 AI701722 AK097817 AK123326 AK312488 BAG35390 AW511101 BC136458 AAI36459 BC136459 AAI36460 X94552 CAA64245 XM_011533648 XP_011531950 XR_940422 NM_000844 NP_000835 NM_181874 NP_870989 NM_181875
Function	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. {ECO:0000269|PubMed:9473604}.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Expressed in many areas of the brain, especially in the cerebral cortex, hippocampus, and cerebellum. Expression of GRM7 isoforms in non-neuronal tissues appears to be restricted to isoform 3 and isoform 4. {ECO:0000269|PubMed:12052533, ECO:0000269|PubMed:8840028}.
Top Pathways	Glutamatergic synapse, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Metabotropic Glutamate Receptor 7 full length protein - ab158591 from Abcam Category Protein Source Wheat germ Species Human

Human Metabotropic Glutamate Receptor 7 protein fragment - ab158592 from Abcam Category Protein Source Wheat germ Species Human

GRM7 / MGLUR7 Antibody Blocking Peptide - LS-E4616 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GRM7 / MGLUR7 Antibody Blocking Peptide - LS-E29568 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GRM7 / MGLUR7 Antibody Blocking Peptide - LS-E29569 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GRM7 / MGLUR7 Antibody Blocking Peptide - LS-E21808 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GRM7 / MGLUR7 Antibody Blocking Peptide - LS-E28598 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GRM7 / MGLUR7 Antibody Blocking Peptide - LS-E27016 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GRM7 / MGLUR7 Antibody Blocking Peptide - LS-E29572 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human mGluR7 Protein - H00002917-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

mGluR7 Recombinant Protein - H00002917-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

Recombinant Human mGluR7 Protein - H00002917-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

GRM7-Antibody-N-term-Blocking-Peptide - BP16975a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

mGluR7 blocking peptide - GTX31060-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat

GRM7 Blocking Peptide - 33R-3808 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

mGLUR7 Blocking Peptide - abx062702 from Abbexa Category Peptide Species Human, Mouse, Rat, Dog, Rabbit

Metabotropic Glutamate Receptor 7 Peptide - AC21-1841-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

mGluR7 / GRM7 - H00002917-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

mGluR7 / GRM7 - H00002917-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

mGluR7 / GRM7 - H00002917-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

mGluR7 / GRM7 - H00002917-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

GRM7 Peptide - 46-978P from ProSci Category Peptide Species Human

mGLUR7 Blocking Peptide - CBP1508 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Dog, Rabbit

mGluR-7 (E894) Peptide - BS1147P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

mGluR-7 (K389) Peptide - BS2810P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

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