GRM7

Gene Symbol	GRM7
Entrez Gene	2917
Alt Symbol	GLUR7, GPRC1G, MGLU7, MGLUR7, PPP1R87
Species	Human
Gene Type	protein-coding
Description	glutamate receptor, metabotropic 7
Other Description	metabotropic glutamate receptor 7|protein phosphatase 1, regulatory subunit 87
Swissprots	Q8NFS3 Q8NFS4 Q8NFS2 Q14831
Accessions	CCQ42994 EAW63933 EAW63934 EAW63935 Q14831 AB209214 BAD92451 AI701722 AK097817 AK123326 AK312488 BAG35390 AW511101 BC136458 AAI36459 BC136459 AAI36460 X94552 CAA64245 XM_011533648 XP_011531950 XR_940422 NM_000844 NP_000835 NM_181874 NP_870989 NM_181875
Function	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. {ECO:0000269|PubMed:9473604}.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Expressed in many areas of the brain, especially in the cerebral cortex, hippocampus, and cerebellum. Expression of GRM7 isoforms in non-neuronal tissues appears to be restricted to isoform 3 and isoform 4. {ECO:0000269|PubMed:12052533, ECO:0000269|PubMed:8840028}.
Top Pathways	Glutamatergic synapse, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

mGluR-7 CRISPR/Cas9 KO Plasmid (h) - sc-406953 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

mGluR-7 HDR Plasmid (h) - sc-406953-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

mGluR-7 Double Nickase Plasmid (h) - sc-406953-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

mGluR-7 Double Nickase Plasmid (h2) - sc-406953-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

mGluR-7 CRISPR Activation Plasmid (h) - sc-406953-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

mGluR-7 CRISPR Activation Plasmid (h2) - sc-406953-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

mGluR-7 Lentiviral Activation Particles (h) - sc-406953-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

mGluR-7 Lentiviral Activation Particles (h2) - sc-406953-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

mGluR-7 siRNA (h) - sc-61038 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

mGluR-7 shRNA Plasmid (h) - sc-61038-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

mGluR-7 shRNA (h) Lentiviral Particles - sc-61038-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

mGluR7 RNAi - H00002917-R05 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

mGluR7 RNAi - H00002917-R04 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU068401 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9706 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9706 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08680 from Sigma-Aldrich Category miRNA

GRM7 siRNA (Human) - CRH1970 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

mGluR7 RNAi - H00002917-R06 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

GRM7 - MBS8200563 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

mGluR-7 CRISPR/Cas9 KO Plasmid (h2) - sc-406953-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

mGluR-7 HDR Plasmid (h2) - sc-406953-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human GRM7 (NM_000844.3) - SHH308158 from Creative biogene Category siRNA Species Reactivities Human

Human GRM7 siRNA - orb262472 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

GRM7 shRNA Plasmid (Human) - CHH1970 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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