Gene Symbol | GPD1L |
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Entrez Gene | 23171 |
Alt Symbol | GPD1-L |
Species | Human |
Gene Type | protein-coding |
Description | glycerol-3-phosphate dehydrogenase 1-like |
Other Description | glycerol-3-phosphate dehydrogenase 1-like protein |
Swissprots | Q14702 Q8N335 A8K9U3 Q9BRM5 |
Accessions | EAW64421 EAW64422 Q8N335 AI080105 AK074221 AK125404 BAG54194 AK292808 BAF85497 BC006168 AAH06168 BC028726 AAH28726 BX283865 D42047 BAA07648 DA318838 XM_005264983 XP_005265040 XM_006713068 XP_006713131 NM_015141 NP_055956 |
Function | Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L. {ECO:0000269|PubMed:19666841, ECO:0000269|PubMed:19745168}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17967977}. Note=Localized to the region of the plasma membrane. |
Tissue Specificity | Most highly expressed in heart tissue, with lower levels in the skeletal muscle, kidney, lung and other organs. {ECO:0000269|PubMed:17967977}. |
Top Pathways | Glycerophospholipid metabolism |
Human GPD1L full length protein - ab113595 from Abcam
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GPD1L Antibody Blocking Peptide - LS-E441 from LifeSpan Bioscience
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GPD1L Antibody Blocking Peptide - LS-E19921 from LifeSpan Bioscience
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GPD1L Recombinant Protein - H00023171-P01 from Novus Biologicals
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Recombinant Human GPD1L Protein - NBP1-72456 from Novus Biologicals
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GPD1L-Antibody-N-term-Blocking-peptide - BP10723a from Abgent, a WuXi AppTec company
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ARF3 protein (His tag) - 80R-1971 from Fitzgerald
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GPD1L Blocking Peptide - 33R-2538 from Fitzgerald
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GPD1L protein (His tag) - 80R-1970 from Fitzgerald
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GPD1L (1-351, His-tag) - AR50039PU-N from Acris Antibodies
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GPD1L (1-351, His-tag) - AR50039PU-S from Acris Antibodies
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GPD1L - H00023171-P01-10 from Acris Antibodies
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GPD1L - H00023171-P01-25 from Acris Antibodies
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GPD1L, 1-351aa, Human, His tag, E.coli - 01-P1214 from ARP American Research Products
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GPD1L fusion protein - ag11544 from Proteintech Group
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GPD1L fusion protein - Ag10977 from Proteintech Group
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GPD1L Human - ENPS-178 from NeoScientific
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GPD1L, 1-351aa, Recombinant Protein - GWB-P0824E from Genway Biotech
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Recombinant Human GPD1L, His-tagged - GPD1L-28584TH from Creative Biomart
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Recombinant Human Glycerol-3-Phosphate Dehydrogenase 1-Like, His-tagged - GPD1L-6866H from Creative Biomart
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GPD1L 1-351aa - CMB-1047 from Reagent Proteins
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Recombinant Human Glycerol-3-phosphate dehydrogenase 1-like protein(GPD1L) - CSB-YP854029HU CSB-EP854029HU CSB-BP854029HU CSB-MP854029HU from Cusabio
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GPD1L, 1-351aa, Human, His tag, E.coli - ATGP1214 from ATGen
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GPD1L - TP306131 from Acris Antibodies
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GPD1L Protein - NBP1-81548PEP from Novus Biologicals
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