| Gene Symbol |
Foxk1
|
| Entrez Gene |
17425
|
| Alt Symbol |
A630048H08Rik, AI463295, ENSMUSG00000075577, Gm10868, Mnf
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
forkhead box K1
|
| Other Description |
forkhead box protein K1|myocyte nuclear factor
|
| Swissprots |
Q3UHI6 P42128 O35939 Q3UN67
|
| Accessions |
EDL19101 P42128 AK041945 AK144418 BAE25880 AK147375 BAE27871 BB646926 BC002273 AAH02273 BC060238 BC156273 AAI56274 BE690639 CB249706 L26507 AAA37529 U95016 AAB69641 XM_006504654 XP_006504717 NM_010812 NM_199068 NP_951031
|
| Function |
Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Has a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli. {ECO:0000269|PubMed:8007964, ECO:0000269|PubMed:9271401}.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Expressed in tissues and cells in which the myoglobin gene is transcriptionally active including cardiac and skeletal myocytes, brain and kidney. In the adult brain, expressed in the piriform cortex and the indusium griseum. In the hippocampus, expression is localized to the dentate gyrus and CA3 area. In the cerebellum, expression is confined to the Purkinje cell layer. {ECO:0000269|PubMed:16376864, ECO:0000269|PubMed:8007964, ECO:0000269|PubMed:9271401}.
|