| Gene Symbol |
AP1S3
|
| Entrez Gene |
130340
|
| Alt Symbol |
PSORS15
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
adaptor-related protein complex 1, sigma 3 subunit
|
| Other Description |
AP-1 complex subunit sigma-3|adapter-related protein complex 1 subunit sigma-1C|adaptor protein complex AP-1 sigma-1C subunit|adaptor-related protein complex 1 subunit sigma-1C|clathrin assembly protein complex 1 sigma-1C small chain|golgi adaptor HA1/AP1 adaptin sigma-1C subunit|sigma 1C subunit of AP-1 clathrin
|
| Swissprots |
B4DQZ1 Q96DD1 Q8WTY1 Q96PC3
|
| Accessions |
AAY24166 AAY24244 EAW70813 EAW70814 EAW70815 EAW70816 Q96PC3 AF393369 AAL09586 AK025338 AK299026 BAG61103 BC009606 AAH09606 BC021898 AAH21898 BE856458 BG177582 BG340480 XM_011510600 XP_011508902 NM_001039569 NP_001034658 NR_110905 NR_110906 NM_178814
|
| Function |
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Involved in TLR3 trafficking (PubMed:24791904). {ECO:0000269|PubMed:24791904}.
|
| Subcellular Location |
Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
|
| Tissue Specificity |
Widely expressed.
|
| Top Pathways |
Lysosome
|