Gene Symbol | AP1S3 |
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Entrez Gene | 130340 |
Alt Symbol | PSORS15 |
Species | Human |
Gene Type | protein-coding |
Description | adaptor-related protein complex 1, sigma 3 subunit |
Other Description | AP-1 complex subunit sigma-3|adapter-related protein complex 1 subunit sigma-1C|adaptor protein complex AP-1 sigma-1C subunit|adaptor-related protein complex 1 subunit sigma-1C|clathrin assembly protein complex 1 sigma-1C small chain|golgi adaptor HA1/AP1 adaptin sigma-1C subunit|sigma 1C subunit of AP-1 clathrin |
Swissprots | B4DQZ1 Q96DD1 Q8WTY1 Q96PC3 |
Accessions | AAY24166 AAY24244 EAW70813 EAW70814 EAW70815 EAW70816 Q96PC3 AF393369 AAL09586 AK025338 AK299026 BAG61103 BC009606 AAH09606 BC021898 AAH21898 BE856458 BG177582 BG340480 XM_011510600 XP_011508902 NM_001039569 NP_001034658 NR_110905 NR_110906 NM_178814 |
Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Involved in TLR3 trafficking (PubMed:24791904). {ECO:0000269|PubMed:24791904}. |
Subcellular Location | Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. |
Tissue Specificity | Widely expressed. |
Top Pathways | Lysosome |
AP1S3 Antibody Blocking Peptide - LS-E190 from LifeSpan Bioscience
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AP1S3-Antibody-N-term-Blocking-peptide - BP10390a from Abgent, a WuXi AppTec company
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Recombinant human AP-1 complex subunit sigma-3 (OPCA00008) - OPCA00008 from Aviva Systems Biology
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Human AP1S3 protein - orb244018 from Biorbyt
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AP1S3 fusion protein - ag10777 from Proteintech Group
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AP1S3 fusion protein - Ag10751 from Proteintech Group
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Recombinant human AP-1 complex subunit sigma-3 - CSB-YP001868HU CSB-BP001868HU CSB-MP001868HU from Cusabio
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Recombinant human AP-1 complex subunit sigma-3 - CSB-EP001868HU from Cusabio
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Recombinant Human AP-1 complex subunit sigma-3(AP1S3) - CSB-YP839389HU CSB-EP839389HU CSB-BP839389HU CSB-MP839389HU from Cusabio
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AP-1 complex subunit sigma-3 - RPC140168 from Biomatik
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AP-1 complex subunit sigma-3, Recombinant Protein - MBS1265400 from MyBioSource
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AP-1 complex subunit sigma-3 (AP1S3) , Recombinant Protein - MBS1302564 from MyBioSource
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AP1S3 Recombinant Protein Antigen - NBP2-49493PEP from Novus Biologicals
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AP1S3 Peptide, Human - M34GP00717H from Creative Peptides
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Recombinant human AP-1 complex subunit sigma-3 - AP70038 from Signalway Antibody
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Recombinant Human AP-1 complex subunit sigma-3 (AP1S3) - RPC20909 from Biomatik
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Recombinant Human AP1S3 Protein (1-104 aa), GST-tagged - AP1S3-330H from Creative Biomart
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