| Gene Symbol | FCAR |
|---|---|
| Entrez Gene | 2204 |
| Alt Symbol | CD89, CTB-61M7.2, FcalphaRI |
| Species | Human |
| Gene Type | protein-coding |
| Description | Fc fragment of IgA, receptor for |
| Other Description | Fc alpha receptor|immunoglobulin alpha Fc receptor |
| Swissprots | Q92587 Q1AJL9 Q1AJL8 Q9UEK0 Q15728 Q53X38 Q13603 Q92590 P24071 Q15727 Q13604 Q1AJL7 Q53X39 Q92592 Q92593 Q92588 |
| Accessions | ABK41921 ABO30565 ABO30566 AFV74783 BAB64914 CAA61039 EAW72291 EAW72292 EAW72293 EAW72294 EAW72295 EAW72296 EAW72297 EAW72298 EAW72299 EAW72300 EAW72301 EAW72302 EAW72303 EAW72304 EAW72305 EAW72306 EAW72307 P24071 AK290922 BAF83611 BC027953 AAH27953 BX643574 CV029531 D87853 BAA13471 D87854 BAA13472 D87855 BAA13473 D87856 BAA13474 D87857 BAA13475 D87858 BAA13476 D87859 BAA13477 D87860 BAA13478 D87861 BAA13479 D87862 BAA13480 DQ075334 AAZ76577 DQ075335 AAZ76578 DQ075336 AAZ76579 DQ075337 AAZ76580 DQ075338 AAZ76581 DQ075339 AAZ76582 DQ890935 ABM81861 DQ894098 ABM85024 HG511027 S82919 AAD14421 U43677 AAC50595 U43774 AAC50639 U56236 AAB00566 U56237 AAB00567 X90753 CAA62276 X92558 X92559 X92560 X92561 X92562 XM_011526625 XP_011524927 XM_011526626 XP_011524928 XM_011547517 XP_011545819 XM_011547518 XP_011545820 XM_011547519 XP_011545821 XM_011547554 XP_011545856 XM_011547555 XP_011545857 XM_011547562 XP_011545864 XM_011547563 XP_011545865 XM_011547566 XP_011545868 XM_011547567 XP_011545869 XM_011547573 XP_011545875 XM_011547574 XP_011545876 XM_011547578 XP_011545880 XM_011547579 XP_011545881 XM_011547803 XP_011546105 XM_011547804 XP_011546106 XM_011548553 XP_011546855 XM_011548554 XP_011546856 XM_011548697 XP_011546999 XM_011548698 XP_011547000 XM_011548699 XP_011547001 NM_002000 NP_001991 NM_133269 NP_579803 NM_133271 NP_579805 NM_133272 NP_579806 NM_133273 NP_579807 NM_133274 NP_579808 NM_133277 NP_579811 NM_133278 NP_579812 NM_133279 NM_133280 |
| Function | Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. {ECO:0000269|PubMed:12768205}. |
| Subcellular Location | Isoform B-delta-S2: Secreted. |
| Tissue Specificity | Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces. {ECO:0000269|PubMed:8666819, ECO:0000269|PubMed:8836118}. |
| Top Pathways | Phagosome, Staphylococcus aureus infection |