Gene Symbol |
UGT2B10
|
Entrez Gene |
7365
|
Alt Symbol |
UDPGT2B10
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
UDP glucuronosyltransferase 2 family, polypeptide B10
|
Other Description |
UDP-glucuronosyltransferase 2B10|UDPGT 2B10
|
Swissprots |
A8K9M3 P36537 Q14CR8 B4DPP1
|
Accessions |
EAX05576 EAX05577 EAX05578 P36537 AK222839 BAD96559 AK222872 BAD96592 AK292738 BAF85427 AK298432 BAG60653 BC113649 AAI13650 CD013994 NM_001075 NP_001066 NM_001144767 NP_001138239 NM_001290091 NP_001277020
|
Function |
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
|
Subcellular Location |
Microsome membrane {ECO:0000305}; Single- pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
|
Top Pathways |
Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450
|