Gene Symbol | GBP7 |
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Entrez Gene | 388646 |
Alt Symbol | GBP4L |
Species | Human |
Gene Type | protein-coding |
Description | guanylate binding protein 7 |
Other Description | GBP-7|GTP-binding protein 7|guanine nucleotide-binding protein 7|guanylate-binding protein 7 |
Swissprots | Q8N8V2 |
Accessions | EAW73145 Q8N8V2 AK096141 BAC04709 BC156123 AAI56124 BC157015 AAI57016 NM_207398 NP_997281 |
Function | Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}. |
GBP7 CRISPR/Cas9 KO Plasmid (h) - sc-409463 from Santa Cruz Biotechnology
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GBP7 HDR Plasmid (h) - sc-409463-HDR from Santa Cruz Biotechnology
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GBP7 Double Nickase Plasmid (h) - sc-409463-NIC from Santa Cruz Biotechnology
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GBP7 Double Nickase Plasmid (h2) - sc-409463-NIC-2 from Santa Cruz Biotechnology
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GBP7 CRISPR Activation Plasmid (h) - sc-409463-ACT from Santa Cruz Biotechnology
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GBP7 CRISPR Activation Plasmid (h2) - sc-409463-ACT-2 from Santa Cruz Biotechnology
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GBP7 Lentiviral Activation Particles (h) - sc-409463-LAC from Santa Cruz Biotechnology
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GBP7 Lentiviral Activation Particles (h2) - sc-409463-LAC-2 from Santa Cruz Biotechnology
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GBP7 siRNA (h) - sc-78654 from Santa Cruz Biotechnology
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GBP7 shRNA Plasmid (h) - sc-78654-SH from Santa Cruz Biotechnology
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GBP7 shRNA (h) Lentiviral Particles - sc-78654-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN9174 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9174 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03146 from Sigma-Aldrich
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GBP7 siRNA (Human) - CRJ7824 from Cohesion Biosciences
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GBP7 - MBS8240309 from MyBioSource
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shRNA set against Human GBP7 (NM_207398.2) - SHH299850 from Creative biogene
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Human GBP7 siRNA - orb278325 from Biorbyt
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GBP7 shRNA Plasmid (Human) - CHJ7824 from Cohesion Biosciences
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GBP7 miRNA 3'UTR clone - MiUTR1H-03976 from Creative biogene
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