Gene Symbol |
Akr1b7
|
Entrez Gene |
11997
|
Alt Symbol |
AR, Avdp, MVDP
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
aldo-keto reductase family 1, member B7
|
Other Description |
aldehyde reductase|aldose reductase-related protein 1|androgen regulated vas deferens protein|vas deferens androgen-dependent protein
|
Swissprots |
P21300
|
Accessions |
AAA39774 EDL13689 P21300 AK002705 BAB22299 AK033773 AK147775 BAE28129 BC086929 AAH86929 CN833345 J05663 AAA39773 NM_009731 NP_033861
|
Function |
Reduces a broad range of aliphatic and aromatic aldehydes to the corresponding alcohols. May play a role in the metabolism of xenobiotic aromatic aldehydes (By similarity). The role of MVDP in sperm maturation and storage may be related to its potential capacity to produce fructose, or MVDP may play an osmoregulatory role by producing sorbitol. {ECO:0000250}.
|
Subcellular Location |
Cytoplasm {ECO:0000250}.
|
Top Pathways |
Pentose and glucuronate interconversions, Glycerolipid metabolism, Galactose metabolism, Fructose and mannose metabolism
|