| Gene Symbol | GABRR2 |
|---|---|
| Entrez Gene | 2570 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| Other Description | GABA-C receptor, rho-2 subunit|gamma-aminobutyric acid receptor subunit rho-2 |
| Swissprots | Q9H153 A2BDE4 P28476 |
| Accessions | EAW48557 P28476 AK293751 BAG57173 BC130352 AAI30353 BC130354 AAI30355 BX490975 DA863180 M86868 AAA52510 XM_011535713 XP_011534015 XM_011535714 XP_011534016 XM_011535715 XP_011534017 XM_011535716 XP_011534018 XM_011535717 XP_011534019 XM_011535718 XP_011534020 NM_002043 NP_002034 |
| Function | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-2 GABA receptor could play a role in retinal neurotransmission. |
| Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| Top Pathways | GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction |