Gene Symbol | GABRR2 |
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Entrez Gene | 2570 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
Other Description | GABA-C receptor, rho-2 subunit|gamma-aminobutyric acid receptor subunit rho-2 |
Swissprots | Q9H153 A2BDE4 P28476 |
Accessions | EAW48557 P28476 AK293751 BAG57173 BC130352 AAI30353 BC130354 AAI30355 BX490975 DA863180 M86868 AAA52510 XM_011535713 XP_011534015 XM_011535714 XP_011534016 XM_011535715 XP_011534017 XM_011535716 XP_011534018 XM_011535717 XP_011534019 XM_011535718 XP_011534020 NM_002043 NP_002034 |
Function | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-2 GABA receptor could play a role in retinal neurotransmission. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Top Pathways | GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction |
GABA C Rρ2 siRNA (h) - sc-105385 from Santa Cruz Biotechnology
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GABA C Rρ2 shRNA Plasmid (h) - sc-105385-SH from Santa Cruz Biotechnology
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GABA C Rρ2 shRNA (h) Lentiviral Particles - sc-105385-V from Santa Cruz Biotechnology
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GABA-A R rho 2 RNAi - H00002570-R01 from Novus Biologicals
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MISSION® esiRNA - EHU014301 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9059 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9059 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01561 from Sigma-Aldrich
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GABRR2 siRNA (Human) - CRH1708 from Cohesion Biosciences
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GABRR2 - MBS8203058 from MyBioSource
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shRNA set against Human GABRR2 (NM_002043.3) - SHH298641 from Creative biogene
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Human GABRR2 siRNA - orb262210 from Biorbyt
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GABRR2 shRNA Plasmid (Human) - CHH1708 from Cohesion Biosciences
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GABRR2 miRNA 3'UTR clone - MiUTR3H-00850 from Creative biogene
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