| Gene Symbol | ATP1B1 |
|---|---|
| Entrez Gene | 481 |
| Alt Symbol | ATP1B |
| Species | Human |
| Gene Type | protein-coding |
| Description | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| Other Description | Beta 1-subunit of Na(+),K(+)-ATPase|Na, K-ATPase beta-1 polypeptide|adenosinetriphosphatase|sodium pump subunit beta-1|sodium-potassium ATPase subunit beta 1 (non-catalytic)|sodium/potassium-dependent ATPase beta-1 subunit|sodium/potassium-transporting ATPase beta-1 chain|sodium/potassium-transporting ATPase subunit beta-1 |
| Swissprots | P05026 Q5TGZ3 |
| Accessions | AAA36352 CAA35040 CBX47475 EAW90832 EAW90833 P05026 AA507932 AA514770 AK290181 BAF82870 AK296059 BAG58822 AK316043 BAH14414 AY545986 AAT11781 AY946016 AAX55911 BC000006 AAH00006 BE223067 BG702024 BM762099 BQ934151 BT009787 AAP88789 CD106723 CD722755 CR407616 CAG28544 U16799 AAC50132 NM_001677 NP_001668 NM_001001787 |
| Function | This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. {ECO:0000269|PubMed:19694409}. |
| Subcellular Location | Cell membrane; Single-pass type II membrane protein. |
| Tissue Specificity | Found in most tissues. |
| Top Pathways | Salivary secretion, Cardiac muscle contraction, cAMP signaling pathway, Aldosterone-regulated sodium reabsorption, Thyroid hormone synthesis |