| Gene Symbol | PSMC5 |
|---|---|
| Entrez Gene | 5705 |
| Alt Symbol | S8, SUG-1, SUG1, TBP10, TRIP1, p45, p45/SUG |
| Species | Human |
| Gene Type | protein-coding |
| Description | proteasome (prosome, macropain) 26S subunit, ATPase, 5 |
| Other Description | 26S protease regulatory subunit 8|26S proteasome AAA-ATPase subunit RPT6|MSUG1 protein|Tat-binding protein homolog 10|proteasome 26S ATPase subunit 5|proteasome 26S subunit ATPase 5|proteasome subunit p45|thyroid hormone receptor-interacting protein 1|thyroid receptor interactor 1 |
| Swissprots | P62195 A8K763 O43208 A8K3Z3 |
| Accessions | EAW94269 EAW94270 EAW94271 EAW94272 P62195 AF035309 AAB88187 AI193169 AK095836 AK098484 AK290758 BAF83447 AK291878 BAF84567 BC001932 AAH01932 BC002367 AAH02367 BC127888 BF245599 BP209525 D44467 BAA07919 DA056321 DQ892196 ABM83122 DQ895391 ABM86317 L38810 AAC41735 XM_006721980 XP_006722043 XR_934508 NM_001199163 NP_001186092 NM_002805 NP_002796 |
| Function | The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. |
| Subcellular Location | Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}. |
| Top Pathways | Proteasome, Epstein-Barr virus infection |