KCNIP3

Gene Symbol	KCNIP3
Entrez Gene	30818
Alt Symbol	CSEN, DREAM, KCHIP3
Species	Human
Gene Type	protein-coding
Description	Kv channel interacting protein 3, calsenilin
Other Description	A-type potassium channel modulatory protein 3|DRE-antagonist modulator|calsenilin|calsenilin, presenilin-binding protein, EF hand transcription factor|kv channel-interacting protein 3|potassium channel interacting protein 3
Swissprots	Q9UJ84 Q3YAC4 H7BY46 Q96T40 Q9Y2W7 Q3YAC3 Q53TJ5 Q9UJ85
Accessions	AAY14752 EAX10723 EAX10724 EAX10725 EAX10726 EAX10727 Q9Y2W7 AB209076 BAD92313 AF120102 AAD20350 AF199599 AAF33684 AF367022 AAK53711 AJ131730 CAB56835 AK095539 AK315437 BAG37825 BC012850 AAH12850 BI755669 BT020075 AAV38878 BX491997 DQ148485 AAZ77802 DQ148486 AAZ77803 DQ892078 ABM83004 DQ895271 ABM86197 DQ895316 ABM86242 XR_922912 NM_001034914 NP_001030086 NM_013434 NP_038462
Function	May play a role in the regulation of PSEN2 proteolytic processing and apoptosis. Together with PSEN2 involved in modulation of beta-amyloid formation. {ECO:0000269|PubMed:11259376, ECO:0000269|PubMed:11988022, ECO:0000269|PubMed:9771752}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:18957440}. Cell membrane {ECO:0000269|PubMed:15485870, ECO:0000269|PubMed:18957440}; Lipid-anchor {ECO:0000250}. Endoplasmic reticulum {ECO:0000269|PubMed:18957440}. Golgi apparatus. Nucleus. Note=Also membrane-bound, associated with the plasma membrane (PubMed:15485870). In the presence of PSEN2 associated with the endoplasmic reticulum and Golgi. The sumoylated form is present only in the nucleus. {ECO:0000250, ECO:0000269|PubMed:15485870}.
Tissue Specificity	Highly expressed in brain. Widely expressed at lower levels. Expression levels are elevated in brain cortex regions affected by Alzheimer disease. {ECO:0000269|PubMed:14720210}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CSEN peptide - ab55818 from Abcam Category Peptide Prices $176.00 Sizes 50 µg

CSEN peptide - ab5866 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

Human CSEN full length protein - ab101211 from Abcam Category Protein Source E. coli Species Human

KCNIP3 / Dream / Calsenilin Antibody Blocking Peptide - LS-E3820 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KCNIP3 / Dream / Calsenilin Antibody Blocking Peptide - LS-E27539 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KCNIP3 / Dream / Calsenilin Antibody Blocking Peptide - LS-E27540 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KCNIP3 / Dream / Calsenilin Antibody Blocking Peptide - LS-E11451 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KCNIP3 / Dream / Calsenilin Antibody Blocking Peptide - LS-E11144 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Calsenilin Recombinant Protein - H00030818-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Calsenilin Protein - NBP1-50875 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

KCNIP3-Antibody-C-term-Blocking-peptide - BP13839b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

KChIP3-Antibody-N-term-M1-Blocking-Peptide - BP1572a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CSEN Protein - GTX111911-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

KCNIP3 Protein (OPPA02514) - OPPA02514 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human KCNIP3 protein - orb168687 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli

Human CSEN protein (His Tag) - orb138633 from Biorbyt Category Protein Prices $298.00, $612.00 Sizes 20 μg, 100 μg Source E. coli Species Human

Calsenilin Blocking Peptide - 33R-10894 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

Kcnip3 Blocking Peptide - 33R-7228 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

KCNIP3 protein (His tag) - 80R-1550 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

CSEN Peptide - AC21-2361-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CSEN Peptide - AC21-2362-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Calsenilin (1-256, His-tag) - AR09729PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

Calsenilin (1-256, His-tag) - AR09729PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

Calsenilin - H00030818-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Calsenilin - H00030818-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

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