KCNIP3

Gene Symbol KCNIP3
Entrez Gene 30818
Alt Symbol CSEN, DREAM, KCHIP3
Species Human
Gene Type protein-coding
Description Kv channel interacting protein 3, calsenilin
Other Description A-type potassium channel modulatory protein 3|DRE-antagonist modulator|calsenilin|calsenilin, presenilin-binding protein, EF hand transcription factor|kv channel-interacting protein 3|potassium channel interacting protein 3
Swissprots Q9UJ84 Q3YAC4 H7BY46 Q96T40 Q9Y2W7 Q3YAC3 Q53TJ5 Q9UJ85
Accessions AAY14752 EAX10723 EAX10724 EAX10725 EAX10726 EAX10727 Q9Y2W7 AB209076 BAD92313 AF120102 AAD20350 AF199599 AAF33684 AF367022 AAK53711 AJ131730 CAB56835 AK095539 AK315437 BAG37825 BC012850 AAH12850 BI755669 BT020075 AAV38878 BX491997 DQ148485 AAZ77802 DQ148486 AAZ77803 DQ892078 ABM83004 DQ895271 ABM86197 DQ895316 ABM86242 XR_922912 NM_001034914 NP_001030086 NM_013434 NP_038462
Function May play a role in the regulation of PSEN2 proteolytic processing and apoptosis. Together with PSEN2 involved in modulation of beta-amyloid formation. {ECO:0000269|PubMed:11259376, ECO:0000269|PubMed:11988022, ECO:0000269|PubMed:9771752}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:18957440}. Cell membrane {ECO:0000269|PubMed:15485870, ECO:0000269|PubMed:18957440}; Lipid-anchor {ECO:0000250}. Endoplasmic reticulum {ECO:0000269|PubMed:18957440}. Golgi apparatus. Nucleus. Note=Also membrane-bound, associated with the plasma membrane (PubMed:15485870). In the presence of PSEN2 associated with the endoplasmic reticulum and Golgi. The sumoylated form is present only in the nucleus. {ECO:0000250, ECO:0000269|PubMed:15485870}.
Tissue Specificity Highly expressed in brain. Widely expressed at lower levels. Expression levels are elevated in brain cortex regions affected by Alzheimer disease. {ECO:0000269|PubMed:14720210}.

DREAM CRISPR/Cas9 KO Plasmid (h) - sc-403307 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DREAM HDR Plasmid (h) - sc-403307-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DREAM Double Nickase Plasmid (h) - sc-403307-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DREAM Double Nickase Plasmid (h2) - sc-403307-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DREAM CRISPR Activation Plasmid (h) - sc-403307-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DREAM CRISPR Activation Plasmid (h2) - sc-403307-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DREAM Lentiviral Activation Particles (h) - sc-403307-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DREAM Lentiviral Activation Particles (h2) - sc-403307-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DREAM siRNA (h) - sc-42398 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DREAM shRNA Plasmid (h) - sc-42398-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DREAM shRNA (h) Lentiviral Particles - sc-42398-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Calsenilin RNAi - H00030818-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU074511 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10951 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10951 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

KCNIP3 siRNA (Human) - CRH9345 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Calsenilin RNAi - H00030818-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

KCNIP3, siRNA - MBS8206691 from MyBioSource

Category siRNA
Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human KCNIP3 (NM_013434.4) - SHH323155 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human KCNIP3(NM_013434.4) - SHL183034 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human KCNIP3(NM_001034914.1) - SHL183070 from Creative biogene

Category siRNA
Species Reactivities Human

Human KCNIP3 siRNA - orb269847 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

KCNIP3 shRNA Plasmid (Human) - CHH9345 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KCNIP3 miRNA 3'UTR clone - MiUTR1H-05126 from Creative biogene

Species Reactivities Human

KCNIP3 miRNA 3'UTR clone - MiUTR1H-05127 from Creative biogene

Species Reactivities Human
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