| Gene Symbol | GABRR1 |
|---|---|
| Entrez Gene | 2569 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | gamma-aminobutyric acid (GABA) A receptor, rho 1 |
| Other Description | GABA(A) receptor subunit rho-1|GABA(A) receptor, rho 1|GABA(C) receptor|bA135P14.1 (gamma-aminobutyric acid (GABA) receptor, rho 1)|gamma-aminobutyric acid (GABA) A receptor, rho-1|gamma-aminobutyric acid (GABA) receptor, rho 1|gamma-aminobutyric acid receptor subunit rho-1 |
| Swissprots | Q9BX06 A1L401 B4DQT5 P24046 B7ZBQ7 B4DJK8 |
| Accessions | EAW48558 P24046 AK296124 BAG58870 AK298948 BAG61047 AK313609 AW135923 BC130344 AAI30345 DA753437 DC403980 M62400 AAA52509 XM_006715438 XP_006715501 XM_011535711 XP_011534013 XM_011535712 XP_011534014 NM_001256703 NP_001243632 NM_001256704 NP_001243633 NM_001267582 NP_001254511 NM_002042 NP_002033 |
| Function | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission. |
| Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Highly expressed in the retina and in a lesser extent in brain, lung and thymus. |
| Top Pathways | GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction |