| Gene Symbol | SMARCD1 |
|---|---|
| Entrez Gene | 6602 |
| Alt Symbol | BAF60A, CRACD1, Rsc6p |
| Species | Human |
| Gene Type | protein-coding |
| Description | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
| Other Description | 60 kDa BRG-1/Brm-associated factor subunit A|BRG1-associated factor 60A|SWI/SNF complex 60 kDa subunit A|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1|Swp73-like protein|chromatin remodeling complex BAF60A subunit|mammalian chromatin remodeling complex BRG1-associated factor 60A |
| Swissprots | Q9Y635 Q96GM5 Q92924 A6NN27 |
| Accessions | EAW58120 EAW58121 EAW58122 EAW58123 EAW58124 EAW58125 EAW58126 EAW58127 Q96GM5 AA610093 AF109733 AAD23390 AK130517 AK292700 BAF85389 AK293932 BAG57311 BC000063 BC009368 AAH09368 BE905082 CN272379 DA825057 DB010252 EU447009 ABZ92538 N75126 U66617 AAC50695 XM_005269107 XP_005269164 XM_011538695 XP_011536997 XR_944683 XR_944684 NM_003076 NP_003067 NM_139071 NP_620710 |
| Function | Involved in chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essent |
| Subcellular Location | Nucleus {ECO:0000269|PubMed:8804307, ECO:0000305}. |
| Tissue Specificity | Expressed in all tissues tested, including brain, heart, kidney, liver, lung, muscle, pancreas and placenta. {ECO:0000269|PubMed:8804307}. |
Human-SMARCD1-cDNA-Clone - DC02638 from Abgent, a WuXi AppTec company
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SMARCD1 - MBS1266766 from MyBioSource
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Human SMARCD1 cDNA clone(NM_139071.2) - CDFG008386 from Creative Biomart
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Human SMARCD1 cDNA clone(NM_003076.4) - CDFH018157 from Creative Biomart
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human SMARCD1 ORF clone - CDCH083474 from Creative Biomart
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human SMARCD1 ORF clone - CDCH083475 from Creative Biomart
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human SMARCD1 ORF clone - CDCH083476 from Creative Biomart
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human SMARCD1 ORF clone - CDCH083477 from Creative Biomart
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human SMARCD1 ORF clone - CDCH083478 from Creative Biomart
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human SMARCD1 ORF clone - CDCH083479 from Creative Biomart
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human SMARCD1 ORF clone - CDCH083480 from Creative Biomart
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human SMARCD1 ORF clone - CDCH083481 from Creative Biomart
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Human SMARCD1 ORF Clone(NM_003076.4) - CDCL176362 from Creative Biomart
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Human SMARCD1 ORF Clone(NM_003076.4) - CDCL176363 from Creative Biomart
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Human SMARCD1 ORF Clone(NM_003076.4) - CDCR284794 from Creative Biomart
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Human SMARCD1 ORF Clone(NM_003076.4) - CDCR284795 from Creative Biomart
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Human SMARCD1 ORF Clone(NM_003076.4) - CDCR284796 from Creative Biomart
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Human SMARCD1 ORF Clone(NM_139071.2) - CDCR317200 from Creative Biomart
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Human SMARCD1 ORF Clone(NM_139071.2) - CDCR317201 from Creative Biomart
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human SMARCD1 ORF clone (NM_139071.2) - CDCH083474 from Creative biogene
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human SMARCD1 ORF clone (NM_003076.4) - CDCH083476 from Creative biogene
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Human SMARCD1 ORF Clone (BC009368) - CDCS411130 from Creative biogene
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Human SMARCD1 cDNA Clone(NM_139071.2) - CDFG008386 from Creative biogene
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Human SMARCD1 cDNA Clone(NM_003076.4) - CDFH018157 from Creative biogene
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