| Gene Symbol | PEX26 |
|---|---|
| Entrez Gene | 55670 |
| Alt Symbol | PBD7A, PBD7B, PEX26M1T, Pex26pM1T |
| Species | Human |
| Gene Type | protein-coding |
| Description | peroxisomal biogenesis factor 26 |
| Other Description | peroxin-26|peroxisome assembly protein 26|peroxisome biogenesis disorder, complementation group 8|peroxisome biogenesis disorder, complementation group A|peroxisome biogenesis factor 26 |
| Swissprots | F6UBB5 Q7Z412 Q96B12 Q9NXU0 Q7Z413 Q7Z416 Q7Z414 Q9NWQ0 Q7Z415 |
| Accessions | EAW57782 EAW57783 EAW57784 Q7Z412 AB089678 BAC66616 AB103104 BAC78802 AB103105 BAC78803 AB103106 BAC78804 AB103107 BAC78805 AB103108 BAC78806 AB103109 BAC78807 AB103110 BAC78808 AB242826 BAE72692 AB242827 BAE72693 AB242828 BAE72694 AB242829 BAE72695 AB242830 BAE72696 AI375247 AI636019 AK000065 BAA90920 AK000702 BAA91329 BC016280 AAH16280 BC047320 AAH47320 BG257217 BG910944 BP270408 CA433324 CB989626 CR456362 CAG30248 CU013073 CAK54504 CU013361 CAK54803 DA164404 NM_001127649 NP_001121121 NM_001199319 NP_001186248 NM_017929 NP_060399 |
| Function | Probably required for protein import into peroxisomes. Anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Involved in the import of catalase and proteins containing a PTS2 target sequence, but not in import of proteins with a PTS1 target sequence. {ECO:0000269|PubMed:12717447, ECO:0000269|PubMed:12851857}. |
| Subcellular Location | Peroxisome membrane {ECO:0000269|PubMed:12717447}; Single-pass type II membrane protein {ECO:0000269|PubMed:12717447}. |
| Tissue Specificity | Widely expressed. Highly expressed in kidney, liver, brain and skeletal muscles. Expressed at intermediate level in pancreas, placenta and heart. Weakly expressed in lung. {ECO:0000269|PubMed:12851857}. |
| Top Pathways | Peroxisome |
Peroxin 26 CRISPR/Cas9 KO Plasmid (h) - sc-408486 from Santa Cruz Biotechnology
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Peroxin 26 HDR Plasmid (h) - sc-408486-HDR from Santa Cruz Biotechnology
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Peroxin 26 Double Nickase Plasmid (h) - sc-408486-NIC from Santa Cruz Biotechnology
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Peroxin 26 Double Nickase Plasmid (h2) - sc-408486-NIC-2 from Santa Cruz Biotechnology
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Peroxin 26 CRISPR Activation Plasmid (h) - sc-408486-ACT from Santa Cruz Biotechnology
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Peroxin 26 CRISPR Activation Plasmid (h2) - sc-408486-ACT-2 from Santa Cruz Biotechnology
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Peroxin 26 Lentiviral Activation Particles (h) - sc-408486-LAC from Santa Cruz Biotechnology
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Peroxin 26 Lentiviral Activation Particles (h2) - sc-408486-LAC-2 from Santa Cruz Biotechnology
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Peroxin 26 siRNA (h) - sc-62773 from Santa Cruz Biotechnology
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Peroxin 26 shRNA Plasmid (h) - sc-62773-SH from Santa Cruz Biotechnology
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Peroxin 26 shRNA (h) Lentiviral Particles - sc-62773-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN16640 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16640 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09423 from Sigma-Aldrich
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PEX26 siRNA (Human) - CRJ0822 from Cohesion Biosciences
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shRNA set against Human PEX26 (NM_017929.5) - SHH373756 from Creative biogene
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Human PEX26 siRNA - orb271323 from Biorbyt
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PEX26 shRNA Plasmid (Human) - CHJ0822 from Cohesion Biosciences
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PEX26 miRNA 3'UTR clone - MiUTR3H-10137 from Creative biogene
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PEX26 miRNA 3'UTR clone - MiUTR3H-10138 from Creative biogene
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