BABAM1

Gene Symbol BABAM1
Entrez Gene 29086
Alt Symbol C19orf62, HSPC142, MERIT40, NBA1
Species Human
Gene Type protein-coding
Description BRISC and BRCA1 A complex member 1
Other Description BRCA1-A complex subunit MERIT40|BRISC and BRCA1-A complex member 1|mediator of RAP80 interactions and targeting subunit of 40 kDa|mediator of Rap80 interactions and targeting 40 kDa|new component of the BRCA1 A complex|new component of the BRCA1-A complex|new component of the BRCAA1 A complex
Swissprots Q9P018 Q6FIA0 B4DRY9 B4DVR1 A8MQT0 Q9NWV8
Accessions EAW84584 EAW84585 Q9NWV8 AF161491 AAF29106 AI948445 AJ572521 AK000578 BAA91268 AK025970 AK225047 AK301193 BAG62773 AK308590 AL136692 CAB66627 AM393637 CAL38513 AM393724 CAL38600 BC000788 AAH00788 BC006244 AAH06244 BC091491 AAH91491 BP246573 CR533526 CAG38557 CX866662 NM_001033549 NP_001028721 NM_001288756 NP_001275685 NM_001288757 NP_001275686 NM_014173 NP_054892
Function Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. Probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. In these 2 complexes, it is probably required to maintain the stability of BRE/BRCC45 and help the 'Lys-63'-linked deubiquitinase activity mediated by BRCC3/BRCC36 component. {ECO:0000269|PubMed:19261746, ECO:0000269|PubMed:19261748, ECO:0000269|PubMed:19261749}.
Subcellular Location Cytoplasm. Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs).

C19orf62 CRISPR/Cas9 KO Plasmid (h) - sc-409906 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C19orf62 HDR Plasmid (h) - sc-409906-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C19orf62 Double Nickase Plasmid (h) - sc-409906-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C19orf62 Double Nickase Plasmid (h2) - sc-409906-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C19orf62 CRISPR Activation Plasmid (h) - sc-409906-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C19orf62 CRISPR Activation Plasmid (h2) - sc-409906-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C19orf62 Lentiviral Activation Particles (h) - sc-409906-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C19orf62 Lentiviral Activation Particles (h2) - sc-409906-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C19orf62 siRNA (h) - sc-97426 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C19orf62 shRNA Plasmid (h) - sc-97426-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C19orf62 shRNA (h) Lentiviral Particles - sc-97426-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU081041 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4556 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4556 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02344 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02344

BABAM1 siRNA (Human) - CRH9179 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BABAM1 - MBS8216083 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human BABAM1 (NM_014173.2) - SHH244554 from Creative biogene

Category siRNA
Species Reactivities Human

Human BABAM1 siRNA - orb269681 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BABAM1 shRNA Plasmid (Human) - CHH9179 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

BABAM1 miRNA 3'UTR clone - MiUTR1H-04741 from Creative biogene

Species Reactivities Human

BABAM1 miRNA 3'UTR clone - MiUTR3H-12588 from Creative biogene

Species Reactivities Human
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