Gene Symbol | Gpr119 |
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Entrez Gene | 236781 |
Alt Symbol | - |
Species | Mouse |
Gene Type | protein-coding |
Description | G-protein coupled receptor 119 |
Other Description | G protein-coupled receptor 119|glucose-dependent insulinotropic receptor |
Swissprots | Q7TQP3 Q2ABS2 |
Accessions | Q7TQP3 AB233291 BAE80212 AY288423 AAP72132 BC115557 AAI15558 BC115558 AAI15559 XM_006541488 XP_006541551 NM_181751 NP_861416 |
Function | Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway. {ECO:0000269|PubMed:17289847}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expression restricted to the beta-cells of pancreatic islets. {ECO:0000269|PubMed:17070774, ECO:0000269|PubMed:17289847}. |
Top Pathways | cAMP signaling pathway |
GPR119 CRISPR/Cas9 KO Plasmid (m) - sc-433515 from Santa Cruz Biotechnology
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GPR119 HDR Plasmid (m) - sc-433515-HDR from Santa Cruz Biotechnology
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GPR119 Double Nickase Plasmid (m) - sc-433515-NIC from Santa Cruz Biotechnology
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GPR119 Double Nickase Plasmid (m2) - sc-433515-NIC-2 from Santa Cruz Biotechnology
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GPR119 CRISPR Activation Plasmid (m) - sc-433515-ACT from Santa Cruz Biotechnology
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GPR119 CRISPR Activation Plasmid (m2) - sc-433515-ACT-2 from Santa Cruz Biotechnology
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GPR119 Lentiviral Activation Particles (m) - sc-433515-LAC from Santa Cruz Biotechnology
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GPR119 Lentiviral Activation Particles (m2) - sc-433515-LAC-2 from Santa Cruz Biotechnology
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GPR119 siRNA (m) - sc-60734 from Santa Cruz Biotechnology
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GPR119 shRNA Plasmid (m) - sc-60734-SH from Santa Cruz Biotechnology
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GPR119 shRNA (m) Lentiviral Particles - sc-60734-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN32699 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND32699 from Sigma-Aldrich
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GPR119 siRNA (Mouse) - CRN3279 from Cohesion Biosciences
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GPR119 - MBS8232831 from MyBioSource
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shRNA set against Mouse GPR119 (NM_181751.2) - SHH306150 from Creative biogene
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shRNA set against Mouse Gpr119(NM_181751.2) - SHH097445 from Creative biogene
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Mouse GPR119 siRNA - orb292754 from Biorbyt
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GPR119 shRNA Plasmid (Mouse) - CHN3279 from Cohesion Biosciences
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GPR119 miRNA 3'UTR clone - MiUTR1M-05281 from Creative biogene
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