Gene Symbol |
Taf2
|
Entrez Gene |
319944
|
Alt Symbol |
150kDa, 4732460C16Rik, AI425886, CIF150, TAF2B, TAFII-150, TAFII150
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor
|
Other Description |
TAF(II)150|TBP-associated factor 150 kDa|transcription initiation factor TFIID 150 kDa subunit|transcription initiation factor TFIID subunit 2
|
Swissprots |
Q8C176 Q8BKQ7
|
Accessions |
Q8C176 AK028828 BAC26141 AK051126 BAC34531 AK147903 AK194928 AK198694 BC147638 AAI47639 BC151079 AAI51080 XM_006521076 XP_006521139 XM_006521077 XP_006521140 XM_011245657 XP_011243959 XM_011245658 XP_011243960 NM_001081288 NP_001074757
|
Function |
Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. It requires core promoter-specific cofactors for productive transcription stimulation. TAF2 stabilizes TFIID binding to core promoter (By similarity). {ECO:0000250}.
|
Subcellular Location |
Nucleus {ECO:0000250}.
|
Top Pathways |
Basal transcription factors
|