| Gene Symbol | HK2 |
|---|---|
| Entrez Gene | 3099 |
| Alt Symbol | HKII, HXK2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | hexokinase 2 |
| Other Description | HK II|hexokinase type II|hexokinase-2|hexokinase-2, muscle|muscle form hexokinase |
| Swissprots | P52789 Q9UN82 Q8WU87 D6W5J2 |
| Accessions | AAT38114 AAX93084 AAY24209 ABI49509 BAA04999 CAA86476 CAA86482 CBF63160 CBU88036 EAW99601 EAW99602 EAW99603 P52789 AF086198 AF148513 AAD30174 AI085541 AI278414 AK290357 BAF83046 AW134604 BC021116 AAH21116 BC064369 AAH64369 BM706373 BM912287 CB160837 CR749202 CAH18060 DQ895770 ABM86696 EU176361 ABW03812 XM_005264280 XP_005264337 XM_011532807 XP_011531109 NM_000189 NP_000180 |
| Subcellular Location | Mitochondrion outer membrane {ECO:0000250}. Note=Its hydrophobic N-terminal sequence may be involved in membrane binding. {ECO:0000250}. |
| Tissue Specificity | Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. |
| Top Pathways | Glycolysis / Gluconeogenesis, Central carbon metabolism in cancer, Carbohydrate digestion and absorption, Type II diabetes mellitus, Insulin signaling pathway |