Gene Symbol | KCNH6 |
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Entrez Gene | 81033 |
Alt Symbol | ERG-2, ERG2, HERG2, Kv11.2, hERG-2 |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel, voltage gated eag related subfamily H, member 6 |
Other Description | eag-related gene member 2|ether-a-go-go-related protein 2|potassium voltage-gated channel subfamily H member 6|potassium voltage-gated channel, subfamily H (eag-related), member 6|voltage-gated potassium channel subunit Kv11.2 |
Swissprots | Q9H252 Q9BRD7 |
Accessions | EAW94308 EAW94309 EAW94310 Q9H252 AA825356 AF311913 AAG40871 AK090969 BAC03559 AK091877 BAC03764 AK296498 BAG59132 AK298363 BAG60605 BC006334 AAH06334 BE465143 BM561167 CD632730 DB147394 DB506421 DB577720 JF432528 ADZ15745 XM_011525302 XP_011523604 XM_011525303 XP_011523605 XM_011525304 XP_011523606 XM_011525305 XP_011523607 XM_011525306 XP_011523608 XM_011525307 XP_011523609 XM_011525308 XP_011523610 XM_011525309 XP_011523611 XM_011525310 XP_011523612 XM_011525311 XP_011523613 XM_011525312 XP_011523614 XM_011525313 XP_011523615 XR_934568 NM_001278919 NP_001265848 NM_001278920 NP_001265849 NM_030779 NP_110406 NM_173092 NP_775115 |
Function | Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, rectifying current (By similarity). Channel properties may be modulated by cAMP and subunit assembly. {ECO:0000250}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in prolactin-secreting adenomas. {ECO:0000269|PubMed:12634931}. |
KCNH6 CRISPR/Cas9 KO Plasmid (h) - sc-408005 from Santa Cruz Biotechnology
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KCNH6 HDR Plasmid (h) - sc-408005-HDR from Santa Cruz Biotechnology
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KCNH6 Double Nickase Plasmid (h) - sc-408005-NIC from Santa Cruz Biotechnology
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KCNH6 Double Nickase Plasmid (h2) - sc-408005-NIC-2 from Santa Cruz Biotechnology
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KCNH6 CRISPR Activation Plasmid (h) - sc-408005-ACT from Santa Cruz Biotechnology
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KCNH6 CRISPR Activation Plasmid (h2) - sc-408005-ACT-2 from Santa Cruz Biotechnology
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KCNH6 Lentiviral Activation Particles (h) - sc-408005-LAC from Santa Cruz Biotechnology
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KCNH6 Lentiviral Activation Particles (h2) - sc-408005-LAC-2 from Santa Cruz Biotechnology
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KCNH6 siRNA (h) - sc-93962 from Santa Cruz Biotechnology
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KCNH6 shRNA Plasmid (h) - sc-93962-SH from Santa Cruz Biotechnology
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KCNH6 shRNA (h) Lentiviral Particles - sc-93962-V from Santa Cruz Biotechnology
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Kv11.2 RNAi - H00081033-R01 from Novus Biologicals
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MISSION® esiRNA - EHU115031 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10946 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10946 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02761 from Sigma-Aldrich
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KCNH6 siRNA (Human) - CRJ2947 from Cohesion Biosciences
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Kv11.2 RNAi - H00081033-R02 from Novus Biologicals
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KCNH6, siRNA - MBS8201985 from MyBioSource
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shRNA set against Human KCNH6 (NM_173092.1) - SHH323095 from Creative biogene
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shRNA set against Human KCNH6(NM_030779.2) - SHL182640 from Creative biogene
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shRNA set against Human KCNH6(NM_173092.1) - SHL182730 from Creative biogene
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KCNH6 shRNA Plasmid (Human) - CHJ2947 from Cohesion Biosciences
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KCNH6 miRNA 3'UTR clone - MiUTR1H-05113 from Creative biogene
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KCNH6 miRNA 3'UTR clone - MiUTR1H-05114 from Creative biogene
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