| Gene Symbol | TK2 |
|---|---|
| Entrez Gene | 7084 |
| Alt Symbol | MTDPS2, MTTK, SCA31 |
| Species | Human |
| Gene Type | protein-coding |
| Description | thymidine kinase 2, mitochondrial |
| Other Description | mt-TK |
| Swissprots | E9PH08 B7ZAB1 O15238 B4DGJ7 O00142 B4DZK7 |
| Accessions | ADP90814 ADP90815 ADP90816 ADP90817 ADP90818 ADP90819 ADP90820 ADP90821 ADP90822 ADP90823 ADP90824 ADP90825 ADP90826 ADP90827 ADP90828 ADP90829 ADP90830 ADP90831 ADP90832 ADP90833 ADP90834 ADP90835 ADP90836 ADP90837 ADP90838 ADP90839 ADP90840 ADP90841 ADP90842 ADP90843 ADP90844 ADP90845 ADP90846 ADP90847 ADP90848 ADP90849 ADP90850 ADP90851 ADP90852 ADP90853 EAW83013 EAW83014 EAW83015 EAW83016 EAW83017 O00142 AF521891 AAN73847 AK026021 AK026041 AK294627 BAG57808 AK295808 BAG58626 AK302976 BAG64119 AK303590 BAG64606 AK316226 BAH14597 AL038860 BC029263 BC040667 BC113928 BC134344 AAI34345 BC142970 AAI42971 DA500158 U77088 AAC51167 U80628 AAC51168 Y10498 CAA71523 NM_001172643 NP_001166114 NM_001172644 NP_001166115 NM_001172645 NP_001166116 NM_001271934 NP_001258863 NM_001271935 NP_001258864 NM_001272050 NP_001258979 NM_004614 NP_004605 NR_073520 NR_073521 |
| Function | Deoxyribonucleoside kinase that phosphorylates thymidine, deoxycytidine, and deoxyuridine. Also phosphorylates anti-viral and anti-cancer nucleoside analogs. |
| Subcellular Location | Mitochondrion. |
| Tissue Specificity | Predominantly expressed in liver, pancreas, muscle, and brain. |
| Top Pathways | Drug metabolism - other enzymes, Pyrimidine metabolism |