Gene Symbol |
LEFTY2
|
Entrez Gene |
7044
|
Alt Symbol |
EBAF, LEFTA, LEFTYA, TGFB4
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
left-right determination factor 2
|
Other Description |
TGF-beta-4|endometrial bleeding-associated factor|left-right determination factor A|protein lefty-2|protein lefty-A|transforming growth factor beta-4
|
Swissprots |
E9PDM4 B3KNH4 Q8NBQ9 Q5TE89 O00292 O75611 B4E332
|
Accessions |
AAC32600 EAW69766 EAW69767 O00292 AA922485 AF081513 AAD48145 AK027520 BAG51336 AK075344 BAC11556 AK094077 AK304549 BAG65344 BC035718 AAH35718 BC065929 DA269806 JF432712 ADZ15929 U81523 AAB53269 XM_011544266 XP_011542568 NM_001172425 NP_001165896 NM_003240 NP_003231
|
Function |
Required for left-right (L-R) asymmetry determination of organ systems in mammals. May play a role in endometrial bleeding.
|
Subcellular Location |
Secreted.
|
Tissue Specificity |
Mesenchymal cells of the endometrial stroma.
|
Top Pathways |
TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells
|