Gene Symbol | LEFTY2 |
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Entrez Gene | 7044 |
Alt Symbol | EBAF, LEFTA, LEFTYA, TGFB4 |
Species | Human |
Gene Type | protein-coding |
Description | left-right determination factor 2 |
Other Description | TGF-beta-4|endometrial bleeding-associated factor|left-right determination factor A|protein lefty-2|protein lefty-A|transforming growth factor beta-4 |
Swissprots | E9PDM4 B3KNH4 Q8NBQ9 Q5TE89 O00292 O75611 B4E332 |
Accessions | AAC32600 EAW69766 EAW69767 O00292 AA922485 AF081513 AAD48145 AK027520 BAG51336 AK075344 BAC11556 AK094077 AK304549 BAG65344 BC035718 AAH35718 BC065929 DA269806 JF432712 ADZ15929 U81523 AAB53269 XM_011544266 XP_011542568 NM_001172425 NP_001165896 NM_003240 NP_003231 |
Function | Required for left-right (L-R) asymmetry determination of organ systems in mammals. May play a role in endometrial bleeding. |
Subcellular Location | Secreted. |
Tissue Specificity | Mesenchymal cells of the endometrial stroma. |
Top Pathways | TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells |
Lefty-A CRISPR/Cas9 KO Plasmid (h) - sc-403932 from Santa Cruz Biotechnology
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Lefty-A HDR Plasmid (h) - sc-403932-HDR from Santa Cruz Biotechnology
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Lefty-A Double Nickase Plasmid (h) - sc-403932-NIC from Santa Cruz Biotechnology
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Lefty-A Double Nickase Plasmid (h2) - sc-403932-NIC-2 from Santa Cruz Biotechnology
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Lefty-A CRISPR Activation Plasmid (h) - sc-403932-ACT from Santa Cruz Biotechnology
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Lefty-A CRISPR Activation Plasmid (h2) - sc-403932-ACT-2 from Santa Cruz Biotechnology
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Lefty-A Lentiviral Activation Particles (h) - sc-403932-LAC from Santa Cruz Biotechnology
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Lefty-A Lentiviral Activation Particles (h2) - sc-403932-LAC-2 from Santa Cruz Biotechnology
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Lefty-A siRNA (h) - sc-39789 from Santa Cruz Biotechnology
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Lefty-A shRNA Plasmid (h) - sc-39789-SH from Santa Cruz Biotechnology
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Lefty-A shRNA (h) Lentiviral Particles - sc-39789-V from Santa Cruz Biotechnology
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Lefty siRNA (h) - sc-43894 from Santa Cruz Biotechnology
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Lefty shRNA Plasmid (h) - sc-43894-SH from Santa Cruz Biotechnology
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Lefty shRNA (h) Lentiviral Particles - sc-43894-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN11637 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11637 from Sigma-Aldrich
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LEFTY2 siRNA (Human) - CRH4817 from Cohesion Biosciences
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shRNA set against Human LEFTY2 (NM_003240.3) - SHH329479 from Creative biogene
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LEFTY2 shRNA Plasmid (Human) - CHH4817 from Cohesion Biosciences
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LEFTY2 miRNA 3'UTR clone - MiUTR3H-04472 from Creative biogene
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