Gene Symbol | TBL1XR1 |
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Entrez Gene | 79718 |
Alt Symbol | C21, DC42, IRA1, TBLR1 |
Species | Human |
Gene Type | protein-coding |
Description | transducin (beta)-like 1 X-linked receptor 1 |
Other Description | F-box-like/WD repeat-containing protein TBL1XR1|TBL1-related protein 1|nuclear receptor co-repressor/HDAC3 complex subunit|nuclear receptor corepressor/HDAC3 complex subunit TBLR1|transducin beta-like 1X-related protein 1 |
Swissprots | Q9H2I1 Q14DC3 Q9BZK7 Q9H9A1 D3DNQ9 |
Accessions | EAW78437 EAW78438 EAW78439 Q9BZK7 AF086399 AF267864 AAG44733 AF268193 AAG44736 AF314544 AAK00301 AK022956 BAB14331 AK025746 AK296946 BAH12461 AL598314 BC034712 BC048298 AAH48298 BC060320 AAH60320 BC070134 BC092400 BC113421 AAI13422 BX648080 BX648935 DB459301 HQ258622 ADR83374 XM_005247771 XP_005247828 XM_005247772 XP_005247829 XM_005247775 XP_005247832 XM_005247776 XP_005247833 XM_006713745 XP_006713808 XM_006713746 XP_006713809 XM_011513140 XP_011511442 XM_011513141 XP_011511443 XM_011513142 XP_011511444 XM_011513143 XP_011511445 NM_024665 NP_078941 |
Function | F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation. {ECO:0000269|PubMed:14980219}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Wnt signaling pathway |
Human TBLR1 full length protein - ab153511 from Abcam
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Human TBLR1 protein fragment - ab153512 from Abcam
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TBL1XR1 / TBLR1 Antibody Blocking Peptide - LS-E4156 from LifeSpan Bioscience
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TBL1XR1 / TBLR1 Antibody Blocking Peptide - LS-E22609 from LifeSpan Bioscience
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TBLR1 Partial Recombinant Protein - H00079718-Q01 from Novus Biologicals
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Recombinant Human TBLR1 Protein - H00079718-P01 from Novus Biologicals
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TBL1XR1-Antibody-N-term-Blocking-Peptide - BP16411a from Abgent, a WuXi AppTec company
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TBL1X/TBL1XR1 blocking peptide - GTX89952-PEP from GeneTex
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TBL1XR1 Blocking Peptide - 33R-8490 from Fitzgerald
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TBLR1 Blocking Peptide - 33R-10888 from Fitzgerald
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TBL1XR1 - H00079718-P01-10 from Acris Antibodies
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TBL1XR1 - H00079718-P01-25 from Acris Antibodies
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TBL1XR1 - H00079718-Q01-10 from Acris Antibodies
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TBL1XR1 - H00079718-Q01-25 from Acris Antibodies
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Recombinant Human F-box-like/WD repeat-containing protein TBL1XR1(TBL1XR1) - CSB-YP883647HU CSB-EP883647HU CSB-BP883647HU CSB-MP883647HU from Cusabio
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TBLR1 Blocking Peptide - 3699BP-50 from Biovision
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C 21 - 5128 from R&D Systems
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TBL1XR1 Protein - abx164578 from Abbexa
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TBL1XR1 (full length, N-term HIS tag) - TP760864 from Acris Antibodies
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TBLR1, Peptide - MBS843677 from MyBioSource
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TBLR1 Recombinant Protein Antigen - NBP1-89880PEP from Novus Biologicals
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TBL1XR1 Peptide, Human - M34GP15670H from Creative Peptides
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F-box-like/WD repeat-containing protein TBL1XR1 (TBL1XR1), Recombinant Protein - MBS1487110 from MyBioSource
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Protein C21/B27 (B27R), Recombinant Protein - MBS1003988 from MyBioSource
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C 21 - R0979 from Creative Peptides
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