| Gene Symbol |
Cyp1a2
|
| Entrez Gene |
13077
|
| Alt Symbol |
CP12, Cyp1a1, P450-3
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
cytochrome P450, family 1, subfamily a, polypeptide 2
|
| Other Description |
CYPIA2|aromatic compound inducible|cytochrome P450 1A2|cytochrome P450 family 1 subfamily a polypeptide 1|cytochrome P450, 1a2, aromatic compound inducible|cytochrome P450-P2|cytochrome P450-P3
|
| Swissprots |
P00186 Q9QWJ4
|
| Accessions |
AAA37508 AAA39873 ACJ12938 CAA25837 EDL25920 P00186 BC018298 AAH18298 BC054827 AAH54827 K02589 AAA37509 X00479 CAA25156 X04283 CAA27832 NM_009993 NP_034123
|
| Function |
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
|
| Top Pathways |
Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450, Tryptophan metabolism
|