Gene Symbol | Cyp1a2 |
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Entrez Gene | 13077 |
Alt Symbol | CP12, Cyp1a1, P450-3 |
Species | Mouse |
Gene Type | protein-coding |
Description | cytochrome P450, family 1, subfamily a, polypeptide 2 |
Other Description | CYPIA2|aromatic compound inducible|cytochrome P450 1A2|cytochrome P450 family 1 subfamily a polypeptide 1|cytochrome P450, 1a2, aromatic compound inducible|cytochrome P450-P2|cytochrome P450-P3 |
Swissprots | P00186 Q9QWJ4 |
Accessions | AAA37508 AAA39873 ACJ12938 CAA25837 EDL25920 P00186 BC018298 AAH18298 BC054827 AAH54827 K02589 AAA37509 X00479 CAA25156 X04283 CAA27832 NM_009993 NP_034123 |
Function | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation (By similarity). {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
Top Pathways | Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450, Tryptophan metabolism |
Cytochrome P450 1A2 Peptide - AC21-2590-P from Abcore
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Cyp1a2 Peptide - 42-901P from ProSci
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Recombinant Mouse Cytochrome P450 1A2(Cyp1a2) - CSB-YP006396MO CSB-EP006396MO CSB-BP006396MO CSB-MP006396MO from Cusabio
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Cytochrome P450 1A2, Peptide - MBS427521 from MyBioSource
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Cytochrome P450 1A2 (Cyp1a2), Recombinant Protein - MBS717576 from MyBioSource
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