DGKA

Gene Symbol DGKA
Entrez Gene 1606
Alt Symbol DAGK, DAGK1, DGK-alpha
Species Human
Gene Type protein-coding
Description diacylglycerol kinase, alpha 80kDa
Other Description 80 kDa diacylglycerol kinase|DAG kinase alpha|diacylglycerol kinase alpha|diglyceride kinase alpha
Swissprots Q8IZ56 Q8N5Q2 P23743 O75483 O75481 Q3ZE25 O95217 O75482
Accessions EAW96849 EAW96850 EAW96851 P23743 AF064767 AAC34802 AF064768 AAC34803 AF064769 AAC34804 AF064770 AAC34805 AF064771 AAC34806 AI815678 AK122973 AK127093 AK226134 AK303320 BAG64388 AK307685 AK309939 AK310600 AY930112 AAY20994 BC023523 AAH23523 BC031870 AAH31870 BF448612 BM836118 BM910598 BQ943057 DQ891717 ABM82643 DQ894894 ABM85820 X62535 CAA44396 XM_005268688 XP_005268745 XM_005268689 XP_005268746 XM_005268690 XP_005268747 XM_011537990 XP_011536292 XM_011537991 XP_011536293 XM_011537992 XP_011536294 XM_011537993 XP_011536295 XM_011537994 XP_011536296 XM_011537995 XP_011536297 XR_429084 NM_001345 NP_001336 NM_201444 NP_958852 NM_201445 NP_958853 NM_201554 NP_963848
Function Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity.
Tissue Specificity Lymphocytes and oligodendroglial cells.
Top Pathways Choline metabolism in cancer, Glycerolipid metabolism, Glycerophospholipid metabolism, Phosphatidylinositol signaling system