NOX5

Gene Symbol NOX5
Entrez Gene 79400
Alt Symbol -
Species Human
Gene Type protein-coding
Description NADPH oxidase, EF-hand calcium binding domain 5
Other Description NADPH oxidase 5
Swissprots Q9HAM8 Q08AN2 Q96PH2 Q96PH1 Q9H6E0 Q96PJ9 B2RBJ4 Q08AN3 Q8TEQ1 Q96PJ8 Q8TER4
Accessions ABC40743 Q96PH1 AF317889 AAG33638 AF325189 AAK57193 AF325190 AAK57194 AF353088 AAK57338 AF353089 AAK57339 AI091544 AK026011 BAB15319 AK074058 BAB84884 AK074071 BAB84897 AK314689 BAG37241 AY166601 AAO33926 BC125097 AAI25098 BC125098 AAI25099 DA739867 DA868876 DQ413001 ABD92513 NM_001184779 NP_001171708 NM_001184780 NP_001171709 NM_024505 NP_078781 NR_033671 NR_033672
Function Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis. Isoform v2 and isoform v5 are involved in endothelial generation of reactive oxygen species (ROS), proliferation and angiogenesis and contribute to endothelial response to thrombin. {ECO:0000269|PubMed:11483596, ECO:0000269|PubMed:12686516, ECO:0000269|PubMed:17275676}.
Subcellular Location Isoform v5: Endoplasmic reticulum.
Tissue Specificity Mainly expressed in pachytene spermatocytes of testis and in lymphocyte-rich areas of spleen and lymph nodes. Isoform v1 is expressed in spleen. Isoform v2 is expressed in testis. Also detected in ovary, placenta, pancreas, cardiac fibroblasts. Expressed in B-cells and prostate malignant cells. Isoform v1 and isoform v3 are expressed in epithelial colorectal adenocarcinoma cells. Isoform v2 and isoform v4 are expressed in endothelial cells. Isoform v1, isoform v2, isoform v3 and isoform v4 are expressed in pulmonary artery smooth muscle cells. Isoform v2 and isoform v5 are expressed in microvascular endothelial cells (at protein level). {ECO:0000269|PubMed:11376945, ECO:0000269|PubMed:11483596, ECO:0000269|PubMed:12686516, ECO:0000269|PubMed:16179589, ECO:0000269|PubMed:16339585, ECO:0000269|PubMed:17275676}.

Nox5 (H-160) - sc-67006 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Nox5 (H-160): sc-67006. Immunoperoxidase staining of formalin fixed, paraffin-embedded human prostate tissue showing cytoplasmic staining of glandular cells.

Nox5 (W-15) - sc-34707 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-NOX5 antibody - ab198213 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-NOX5 antibody (ab198213) at 1/200 dilutionLane 1 : 293T cell lysateLane 2 : HeLa cell lysateLane 3 : Human testis tissue cell lysateLane 4 : Skov3 cell lysateLane 5 : Raji cell lysateLane 6 : Jurkat cell lysatedeveloped using the ECL technique

Anti-NOX5 antibody - C-terminal - ab191010 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-NOX5 antibody - C-terminal (ab191010) at 0.5 µg/mlLane 1 : 22RV1 cell lysateLane 2 : PANC cell lysateLane 3 : HeLa cell lysateLane 4 : SKOV cell lysateLysates/proteins at 40 µg per lane.

Anti-NOX5 antibody - C-terminal - ab178731 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-NOX5 antibody - C-terminal (ab178731) at 1 µg/ml + Jurkat whole cell lysate at 10 µg

Anti-NOX5 Antibody (aa680-709, AP) - LS-C238124 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOX5 Antibody (aa680-709, Biotin) - LS-C238126 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOX5 Antibody (aa680-709, APC) - LS-C238125 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOX5 Antibody (aa680-709, FITC) - LS-C238127 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOX5 Antibody (aa680-709, Azide-free, HRP) - LS-C248938 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOX5 Antibody (aa680-709, PE) - LS-C238128 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOX5 Antibody (aa434-697) - LS-C311715 from LifeSpan Bioscience

Prices $250.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NOX5 Antibody (aa661-691) - LS-C323403 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOX5 Antibody (aa459-508) - LS-C187174 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Jurkat . NOX5 antibody dilution 1.0 ug/ml.

Anti-NOX5 Antibody (aa680-709) - LS-C162949 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
NOX5 Antibody western blot of CEM cell line lysates (35 ug/lane). The NOX5 antibody detected the NOX5 protein (arrow).

Anti-NOX5 Antibody (aa488-502) - LS-C139719 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
NOX5 antibody (0.5 ug/ml) staining of Human Testis lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-NOX5 Antibody (aa747-765) - LS-C313080 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
NOX5 antibody. IHC(P): Human Breast Cancer Tissue.

NOX5 Antibody - NBP1-80989 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: NOX5 Antibody [NBP1-80989] - staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli, plasma membrane & cytoplasm.

NOX5 Antibody - NBP1-68862 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: NOX5 Antibody [NBP1-68862] - NBP1-68862 (0.5ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

NOX5 Polyclonal Antibody - bs-6845R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Antigen: bs-6845P, 0.2ug/100ul \\nPrimary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; \\nSecondary: HRP conjugated Goat Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000; \\nTMB staining; Read the data in Microplate Reader by 450nm\\n

Anti-NOX5, C-Terminal antibody produced in rabbit - SAB4503153 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-NOX5, N-Terminal: <B>Cat. No. SAB4503153</B>: Immunoblotting analysis of extracts from Jurkat cells, using Anti-NOX5, N-Terminal antibody. The lane on the left was treated with the Anti-NOX5, N-Terminal antibody. The lane on the right (negative control) was treated with both Anti-NOX5, N-Terminal antibody and the synthesized immunogen peptide.

Anti-NOX5 antibody produced in goat - SAB2501641 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-NOX5 <B>Cat. No. SAB2501641</B>: (0.5 μg/mL) staining of Human Testis lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-NOX5 antibody produced in rabbit - HPA019362 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NOX5: <B>Cat. No. HPA019362</B>: Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.

NOX5 Antibody - C-terminal region (ARP49819_P050) - ARP49819_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NOX5-Antibody-C-term - AP13968b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
NOX5 Antibody (C-term) (Cat. #AP13968b) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the NOX5 antibody detected the NOX5 protein (arrow).
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