Gene Symbol | CDKN2D |
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Entrez Gene | 1032 |
Alt Symbol | INK4D, p19, p19-INK4D |
Species | Human |
Gene Type | protein-coding |
Description | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
Other Description | CDK inhibitor p19INK4d|cell cycle inhibitor, Nur77 associating protein|cyclin-dependent kinase 4 inhibitor D|cyclin-dependent kinase 4 inhibitor D p19|inhibitor of cyclin-dependent kinase 4d |
Swissprots | P55273 Q6FGE9 Q13102 |
Accessions | AAC27450 AAD02320 AAM54045 BAC41254 EAW84122 EAW84123 P55273 BC001822 AAH01822 BG719545 BI462387 BI669755 CR542158 CAG46955 DQ892872 ABM83798 DQ892951 ABM83877 DQ896120 ABM87119 U20498 AAA85436 U40343 AAB18139 U49399 AAB03772 NM_001800 NP_001791 NM_079421 NP_524145 |
Function | Interacts strongly with CDK4 and CDK6 and inhibits them. {ECO:0000269|PubMed:7739548, ECO:0000269|PubMed:8741839}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:9482106}. Cytoplasm {ECO:0000269|PubMed:9482106}. |
Top Pathways | Cell cycle |
p19 CRISPR/Cas9 KO Plasmid (h) - sc-401761 from Santa Cruz Biotechnology
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p19 HDR Plasmid (h) - sc-401761-HDR from Santa Cruz Biotechnology
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p19 Double Nickase Plasmid (h) - sc-401761-NIC from Santa Cruz Biotechnology
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p19 Double Nickase Plasmid (h2) - sc-401761-NIC-2 from Santa Cruz Biotechnology
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p19 CRISPR Activation Plasmid (h) - sc-401761-ACT from Santa Cruz Biotechnology
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p19 CRISPR Activation Plasmid (h2) - sc-401761-ACT-2 from Santa Cruz Biotechnology
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p19 Lentiviral Activation Particles (h) - sc-401761-LAC from Santa Cruz Biotechnology
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p19 Lentiviral Activation Particles (h2) - sc-401761-LAC-2 from Santa Cruz Biotechnology
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p19 siRNA (h) - sc-36148 from Santa Cruz Biotechnology
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p19 shRNA Plasmid (h) - sc-36148-SH from Santa Cruz Biotechnology
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p19 shRNA (h) Lentiviral Particles - sc-36148-V from Santa Cruz Biotechnology
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p19 INK4d RNAi - H00001032-R02 from Novus Biologicals
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MISSION® esiRNA - EHU070621 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5868 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5868 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05218 from Sigma-Aldrich
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CDKN2D siRNA (Human) - CRH0745 from Cohesion Biosciences
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p19 INK4d RNAi - H00001032-R01 from Novus Biologicals
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CDKN2D - MBS8222440 from MyBioSource
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p19 CRISPR/Cas9 KO Plasmid (h2) - sc-401761-KO-2 from Santa Cruz Biotechnology
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p19 HDR Plasmid (h2) - sc-401761-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human CDKN2D (NM_001800.3) - SHH260905 from Creative biogene
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shRNA set against Human CDKN2D(NM_001800.3) - SHG165289 from Creative biogene
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CDKN2D shRNA Plasmid (Human) - CHH0745 from Cohesion Biosciences
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CDKN2D miRNA 3'UTR clone - MiUTR1H-02003 from Creative biogene
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