| Gene Symbol | CR2 |
|---|---|
| Entrez Gene | 1380 |
| Alt Symbol | C3DR, CD21, CR, CVID7, SLEB9 |
| Species | Human |
| Gene Type | protein-coding |
| Description | complement component (3d/Epstein Barr virus) receptor 2 |
| Other Description | EBV receptor|complement C3d receptor|complement receptor type 2 |
| Swissprots | Q5SR46 C9JHD2 Q14212 Q53EL2 Q5BKT9 P20023 Q13866 Q5SR48 |
| Accessions | AAB04638 AAG37227 ABK41929 CAA66910 EAW93481 EAW93482 EAW93483 P20023 AI765035 AK223627 BAD97347 AK301496 BAG63007 AU133057 AW303499 BC032548 BC090937 AAH90937 BC136394 AAI36395 BQ004295 J03565 AAA35784 M26004 AAA35786 M26317 S62696 AAB27186 X68990 CAA48779 Y00649 CAA68674 XM_011509206 XP_011507508 NM_001006658 NP_001006659 NM_001877 NP_001868 |
| Function | Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. {ECO:0000269|PubMed:7753047}. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen. |
| Top Pathways | Complement and coagulation cascades, Hematopoietic cell lineage, B cell receptor signaling pathway, Epstein-Barr virus infection |