| Gene Symbol |
CTTNBP2
|
| Entrez Gene |
83992
|
| Alt Symbol |
C7orf8, CORTBP2, Orf4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cortactin binding protein 2
|
| Other Description |
cortactin-binding protein 2
|
| Swissprots |
Q7LG11 Q8WZ74 Q9C0A5 O43389
|
| Accessions |
AAC04501 ABC79049 ABC79051 ABC79053 ABC79055 ABC87052 ABC87054 ABC87056 ABC87058 ABC87060 ABC87062 ABC87064 ABC87066 ABD72182 ABD72184 ABD72186 ABD72188 ABD72190 ABD72192 ABD72194 ABD72196 ABD72198 ABD72200 ABD72202 ABD72204 ABD72206 ABD72208 ABD72210 ABD72212 ABD72214 ABD72216 EAL24352 EAW83532 EAW83533 Q8WZ74 AB051545 BAB21849 AF377960 AAL32176 AK091548 AK096565 BAC04818 AK308081 AL137685 BC019644 BC106000 AAI06001 XM_005250634 XP_005250691 XM_005250635 XP_005250692 XM_011516614 XP_011514916 XM_011516615 XP_011514917 XM_011516616 XP_011514918 XM_011516617 XP_011514919 XM_011516618 XP_011514920 NM_033427 NP_219499
|
| Function |
Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance. {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cell cortex {ECO:0000250}. Cell projection, dendritic spine {ECO:0000250}. Note=Remains associated with dendritic spines even after glutamate stimulation. {ECO:0000250}.
|
| Tissue Specificity |
Highest expression in brain. Also expressed in kidney, pancreas, lung, heart, liver, skeletal muscle and placenta. {ECO:0000269|PubMed:11707066}.
|