| Gene Symbol | OST3 |
|---|---|
| Entrez Gene | 854252 |
| Alt Symbol | - |
| Species | Yeast |
| Gene Type | protein-coding |
| Description | Ost3p |
| Other Description | - |
| Swissprots | D6W2E7 P48439 |
| Accessions | DAA10863 P48439 NM_001183504 NP_014728 |
| Function | Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Top Pathways | N-Glycan biosynthesis, Protein processing in endoplasmic reticulum, Various types of N-glycan biosynthesis |