CRB3

Gene Symbol CRB3
Entrez Gene 92359
Alt Symbol -
Species Human
Gene Type protein-coding
Description crumbs family member 3
Other Description crumbs homolog 3|crumbs protein homolog 3|protein crumbs homolog 3
Swissprots Q8N0V8 Q8WVA0 A8KA91 Q9BUF7 D6W643
Accessions EAW69083 EAW69084 EAW69085 EAW69086 Q9BUF7 AF503290 AAM23013 AK000653 AK292956 BAF85645 AY103469 AAM44074 AY358684 AAQ89047 BC002652 AAH02652 BC018409 AAH18409 BM129809 CN403242 XM_005259680 XP_005259737 NM_139161 NP_631900 NM_174881 NP_777377
Function Involved in the establishment of cell polarity in mammalian epithelial cells. Regulates the morphogenesis of tight junctions. {ECO:0000269|PubMed:12771187, ECO:0000269|PubMed:14718572}.
Subcellular Location Apical cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Localizes primarily to the apical membrane with a small fraction in the upper part of tight junctions of epithelial cells.
Tissue Specificity Preferentially expressed in epithelial tissues. Expressed at high levels in lung, kidney, retina, colon and mammary glands. Expressed at moderate levels in liver, spleen, pancreas, placenta and prostate. {ECO:0000269|PubMed:12527193, ECO:0000269|PubMed:14718572}.
Top Pathways Tight junction

CRB3 CRISPR/Cas9 KO Plasmid (h) - sc-403145 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRB3 HDR Plasmid (h) - sc-403145-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRB3 Double Nickase Plasmid (h) - sc-403145-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRB3 Double Nickase Plasmid (h2) - sc-403145-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRB3 CRISPR Activation Plasmid (h) - sc-403145-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRB3 CRISPR Activation Plasmid (h2) - sc-403145-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRB3 Lentiviral Activation Particles (h) - sc-403145-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRB3 Lentiviral Activation Particles (h2) - sc-403145-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRB3 siRNA (h) - sc-43698 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CRB3 shRNA Plasmid (h) - sc-43698-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CRB3 shRNA (h) Lentiviral Particles - sc-43698-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN6547 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6547 from Sigma-Aldrich

Category ZFN Kit
Prices $4,120.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04727 from Sigma-Aldrich

Category miRNA

CRB3 siRNA (Human) - CRJ4136 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CRB3 - MBS8205003 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CRB3 (NM_139161.3) - SHH269225 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CRB3(NM_139161.3) - SHG197623 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CRB3(NM_174881.2) - SHG197641 from Creative biogene

Category siRNA
Species Reactivities Human

Human CRB3 siRNA - orb274637 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CRB3 shRNA Plasmid (Human) - CHJ4136 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CRB3 miRNA 3'UTR clone - MiUTR1H-02408 from Creative biogene

Species Reactivities Human

CRB3 miRNA 3'UTR clone - MiUTR1H-02409 from Creative biogene

Species Reactivities Human
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