| Gene Symbol | DSG1 |
|---|---|
| Entrez Gene | 1828 |
| Alt Symbol | CDHF4, DG1, DSG, EPKHE, EPKHIA, PPKS1, SPPK1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | desmoglein 1 |
| Other Description | cadherin family member 4|desmoglein-1|desmosomal glycoprotein 1|pemphigus foliaceus antigen |
| Swissprots | B7Z845 Q02413 |
| Accessions | CAA04949 EAX01254 Q02413 AF088042 AF097935 AAC83817 AK302888 BAH13831 BC148374 AAI48375 BC153001 AAI53002 BX476267 CU456411 X56654 CAA39976 NM_001942 NP_001933 |
| Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
| Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction, desmosome. |
| Tissue Specificity | Epidermis, tongue, tonsil and esophagus. |
| Top Pathways | Staphylococcus aureus infection |