SULT2B1

Gene Symbol SULT2B1
Entrez Gene 6820
Alt Symbol HSST2
Species Human
Gene Type protein-coding
Description sulfotransferase family, cytosolic, 2B, member 1
Other Description ST2B1|alcohol sulfotransferase|hydroxysteroid sulfotransferase 2|sulfotransferase 2B1|sulfotransferase family cytosolic 2B member 1
Swissprots O00204 O75814 O00205
Accessions AAC78553 AAC78554 EAW52354 EAW52355 O00204 AK096418 BC034694 AAH34694 HQ447837 ADQ32321 U92314 AAC78498 U92315 AAC78499 XM_005259182 XP_005259239 NM_004605 NP_004596 NM_177973 NP_814444
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol. {ECO:0000269|PubMed:12145317, ECO:0000269|PubMed:9799594}.
Subcellular Location Cytoplasm. Microsome. Nucleus. Note=Phosphorylation of Ser-348 is required for translocation to the nucleus.
Tissue Specificity Expressed highly in placenta, prostate and trachea and lower expression in the small intestine and lung. {ECO:0000269|PubMed:9799594}.
Top Pathways Steroid hormone biosynthesis

Human-SULT2B1-cDNA-Clone - DC06778 from Abgent, a WuXi AppTec company

Prices $492.75
Sizes 10 µg
Species Human
Accession BC034694

SULT2B1 - MBS1271013 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC034694

Human SULT2B1 cDNA clone(NM_177973.1) - CDFG011432 from Creative Biomart

Species Human
Accession NM_177973.1

Human SULT2B1 cDNA clone(NM_004605.2) - CDFH018965 from Creative Biomart

Species Human
Accession NM_004605.2

Human SULT2B1 ORF clone(NM_177973.1) - CDCL186356 from Creative Biomart

Species Human
Accession NM_177973.1

Human SULT2B1 ORF clone(NM_177973.1) - CDCL186357 from Creative Biomart

Species Human
Accession NM_177973.1

Human SULT2B1 ORF Clone(NM_004605.2) - CDCR288441 from Creative Biomart

Species Human
Accession NM_004605.2

Human SULT2B1 ORF Clone(NM_004605.2) - CDCR288442 from Creative Biomart

Species Human
Accession NM_004605.2

Human SULT2B1 ORF Clone(NM_177973.1) - CDCR323042 from Creative Biomart

Species Human
Accession NM_177973.1

Human SULT2B1 ORF Clone(NM_177973.1) - CDCR323043 from Creative Biomart

Species Human
Accession NM_177973.1

Human SULT2B1 ORF Clone(NM_177973.1) - CDCR323044 from Creative Biomart

Species Human
Accession NM_177973.1

human SULT2B1 ORF clone - CDCH087528 from Creative Biomart

Species Human
Accession NM_004605

human SULT2B1 ORF clone - CDCH087529 from Creative Biomart

Species Human
Accession NM_004605

human SULT2B1 ORF clone - CDCH087530 from Creative Biomart

human SULT2B1 ORF clone - CDCH087531 from Creative Biomart

Species Human
Accession NM_004605

Human SULT2B1 Gene cDNA clone plasmid - HG11410-M from Sino Biological

Species Human
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