Gene Symbol |
STXBP3
|
Entrez Gene |
6814
|
Alt Symbol |
MUNC18-3, MUNC18C, PSP, UNC-18C
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
syntaxin binding protein 3
|
Other Description |
platelet Sec1 protein|protein unc-18 homolog 3|protein unc-18 homolog C|syntaxin 4 binding protein|syntaxin-binding protein 3|unc18-3
|
Swissprots |
Q9UPD7 A8K5K7 O00186 Q86YJ3 Q53FW1 A8K269
|
Accessions |
EAW56330 EAW56331 EAW56332 O00186 AF032922 AAC69606 AK223170 BAD96890 AK290134 BAF82823 AK291322 BAF84011 AK312910 BAG35756 BC028028 BC038099 AAH38099 BC047764 AAH47764 CN409056 D63506 BAA19482 NM_007269 NP_009200
|
Function |
Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. {ECO:0000250}.
|
Subcellular Location |
Cytoplasm, cytosol {ECO:0000269|PubMed:10194441}. Cell membrane {ECO:0000269|PubMed:10194441}. Note=In platelets, predominantly cytosolic. Low amounts membrane-associated.
|
Tissue Specificity |
Megakaryocytes and platelets.
|