| Gene Symbol | CNGB1 |
|---|---|
| Entrez Gene | 1258 |
| Alt Symbol | CNCG2, CNCG3L, CNCG4, CNG4, CNGB1B, GAR1, GARP, GARP2, RCNC2, RCNCb, RCNCbeta, RP45 |
| Species | Human |
| Gene Type | protein-coding |
| Description | cyclic nucleotide gated channel beta 1 |
| Other Description | CNG channel beta-1|CNG-4|cyclic nucleotide-gated cation channel 4|cyclic nucleotide-gated cation channel beta-1|cyclic nucleotide-gated cation channel gamma|cyclic nucleotide-gated cation channel modulatory subunit|cyclic nucleotide-gated channel beta-1|glutamic acid-rich protein|glutamic-acid-rich protein |
| Swissprots | H3BN09 Q13059 Q9UMG2 Q14028 Q14029 O43636 |
| Accessions | AAA65619 AAA65620 AAB32607 EAW82957 EAW82958 Q14028 AF042498 AAC04830 BC140364 AAI40365 BC156722 AAI56723 BM672421 BM678849 BQ638084 EL945866 U18945 AAA91633 U58837 AAB63387 XM_006721134 XP_006721197 XM_011522870 XP_011521172 NM_001135639 NP_001129111 NM_001286130 NP_001273059 NM_001297 NP_001288 |
| Function | Subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. |
| Subcellular Location | Membrane; Multi-pass membrane protein. |
| Top Pathways | Olfactory transduction, Phototransduction, cGMP-PKG signaling pathway, cAMP signaling pathway |